Valorization of Polyhydroxybutyrate Biomass for Platform Chemical Generation

Noëlle ten Boer; Erik Keller; Jeroen Siebring; André Heeres; Janneke Krooneman; Kees van der Loo; Lara Witjes

Valorization of Polyhydroxybutyrate Biomass for Platform Chemical Generation

Vertaalde titel van de bijdrage: Valorisatie van polyhydroxybutyraat-houdende biomassa voor de generatie van platformchemicaliën

Noëlle ten Boer, Erik Keller, Jeroen Siebring, André Heeres, Janneke Krooneman, Kees van der Loo, Lara Witjes

University of Groningen, Engineering and Technology Institute Groningen, Products and Processes for Biotechnology in the Biobased Economy
University of Groningen, Faculty of Science and Engineering, Engineering and Technology Institute Groningen, Green Chemical Reaction Engineering

Onderzoeksoutput: Poster › Professional

Samenvatting

De downstream processing van polyhydroxyalkanoaten (PHA’s) is vaak energie-intensief, solvent-intensief en milieutechnisch niet duurzaam. Om de algehele proceshaalbaarheid te verbeteren, is er toenemende belangstelling voor alternatieve valorisatiestrategieën die conventionele polymeerextractie omzeilen. Dit onderzoek richt zich daarom op het directe gebruik van PHA-houdende biomassa als een duurzamere valorisatiestrategie, waarbij conventionele polymeerzuiveringsstappen worden overgeslagen.

In deze studie wordt de biomassa van Caldimonas thermodepolymerans onderzocht voor directe omzetting naar platformchemicaliën. Deze thermofiele, PHA-producerende bacterie accumuleert hoge hoeveelheden polyhydroxybutyraat (P(3HB)) en toont veel potentie voor hoge-celdichtheidscultivatie. Het merendeel van het bestaande onderzoek naar dit organisme is echter beperkt tot kleinschalige fermentaties en Erlenmeyerflask-culturen, terwijl het doel van dit werk is om de biomassaproductie te verhogen en het proces op te schalen.

Vertaalde titel van de bijdrage	Valorisatie van polyhydroxybutyraat-houdende biomassa voor de generatie van platformchemicaliën
Originele taal-2	English
Aantal pagina's	1
Status	Published - 2025
Evenement	PHA Symposium Groningen - Energy Barn @ Zernike, Groningen, Netherlands Duur: 13 jun. 2025 → 13 jun. 2025

Conference

Conference	PHA Symposium Groningen
Land/Regio	Netherlands
Stad	Groningen
Periode	13/06/25 → 13/06/25

Duurzame ontwikkelingsdoelstellingen van de VN

Deze output draagt bij aan de volgende duurzame ontwikkelingsdoelstelling(en)

SDG 03 – Goede gezondheid en welzijn
SDG 06 – Schoon water en sanitaire voorzieningen
SDG 09 – Industrie, innovatie en infrastructuur
SDG 12 – Verantwoordelijke consumptie en productie
SDG 14 – Leven onder water
SDG 15 – Leven op het land

Keywords

microbiologie
fermentatietechnologie
PHA productie
valorisatie

Research Focus Areas Hanze University of Applied Sciences

No Hanze research focus area applicable

Research Focus Areas Research Centre or Centre of Expertise

Life sciences & renewable energy
Biobased chemistry

Publinova thema's

Overig
Techniek

Citeer dit

@conference{916d1a05b95f48a4bd9824febdc9da37,

title = "Valorization of Polyhydroxybutyrate Biomass for Platform Chemical Generation",

abstract = "The downstream processing of PHAs is often energy-intensive, solvent-heavy, and environmentally unsustainable. To improve the overall process viability, alternative valorization strategies that bypass conventional extraction are gaining interest (1). This research focusses on the direct use of PHA-containing biomass to enable a more sustainable valorization strategy by bypassing conventional polymer purification processes. This study investigates the use of Caldimonas thermodepolymerans biomass for its direct conversion into platform chemicals (2). This thermophilic PHA-producing bacterium, accumulates high levels of polyhydroxybutyrate (P(3HB)) and shows promise for high-density cultivation (3). However, most research with this thermophile focusses on small scale fermentations and erlenmeyer batches, whereas our goals are to increase biomass production and scale.",

keywords = "microbiologie, fermentatietechnologie, PHA productie, valorisatie, microbiology, fermentation technology, pha production, valorization",

author = "\{ten Boer\}, No{\"e}lle and Erik Keller and Jeroen Siebring and Andr{\'e} Heeres and Janneke Krooneman and \{van der Loo\}, Kees and Lara Witjes",

year = "2025",

language = "English",

note = "PHA Symposium Groningen ; Conference date: 13-06-2025 Through 13-06-2025",

}

TY - CONF

T1 - Valorization of Polyhydroxybutyrate Biomass for Platform Chemical Generation

AU - ten Boer, Noëlle

AU - Keller, Erik

AU - Siebring, Jeroen

AU - Heeres, André

AU - Krooneman, Janneke

AU - van der Loo, Kees

AU - Witjes, Lara

PY - 2025

Y1 - 2025

N2 - The downstream processing of PHAs is often energy-intensive, solvent-heavy, and environmentally unsustainable. To improve the overall process viability, alternative valorization strategies that bypass conventional extraction are gaining interest (1). This research focusses on the direct use of PHA-containing biomass to enable a more sustainable valorization strategy by bypassing conventional polymer purification processes. This study investigates the use of Caldimonas thermodepolymerans biomass for its direct conversion into platform chemicals (2). This thermophilic PHA-producing bacterium, accumulates high levels of polyhydroxybutyrate (P(3HB)) and shows promise for high-density cultivation (3). However, most research with this thermophile focusses on small scale fermentations and erlenmeyer batches, whereas our goals are to increase biomass production and scale.

AB - The downstream processing of PHAs is often energy-intensive, solvent-heavy, and environmentally unsustainable. To improve the overall process viability, alternative valorization strategies that bypass conventional extraction are gaining interest (1). This research focusses on the direct use of PHA-containing biomass to enable a more sustainable valorization strategy by bypassing conventional polymer purification processes. This study investigates the use of Caldimonas thermodepolymerans biomass for its direct conversion into platform chemicals (2). This thermophilic PHA-producing bacterium, accumulates high levels of polyhydroxybutyrate (P(3HB)) and shows promise for high-density cultivation (3). However, most research with this thermophile focusses on small scale fermentations and erlenmeyer batches, whereas our goals are to increase biomass production and scale.

KW - microbiologie

KW - fermentatietechnologie

KW - PHA productie

KW - valorisatie

KW - microbiology

KW - fermentation technology

KW - pha production

KW - valorization

M3 - Poster

T2 - PHA Symposium Groningen

Y2 - 13 June 2025 through 13 June 2025

ER -

Valorization of Polyhydroxybutyrate Biomass for Platform Chemical Generation

Samenvatting

Conference

Duurzame ontwikkelingsdoelstellingen van de VN

Keywords

Research Focus Areas Hanze University of Applied Sciences

Research Focus Areas Research Centre or Centre of Expertise

Publinova thema's

Vingerafdruk

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