Unidirectional rotary motion in achiral molecular motors

Jos C.M. Kistemaker; Peter Štacko; Johan Visser; Ben L. Feringa

doi:10.1038/nchem.2362

Unidirectional rotary motion in achiral molecular motors

Jos C.M. Kistemaker
, Peter Štacko
, Johan Visser
, Ben L. Feringa

Stratingh Institute, University of Groningen

Onderzoeksoutput: Article › Academic › peer review

Samenvatting

Control of the direction of motion is an essential feature of biological rotary motors and results from the intrinsic chirality of the amino acids from which the motors are made. In synthetic autonomous light-driven rotary motors, point chirality is transferred to helical chirality, and this governs their unidirectional rotation. However, achieving directional rotary motion in an achiral molecular system in an autonomous fashion remains a fundamental challenge. Here, we report an achiral molecular motor in which the presence of a pseudo-asymmetric carbon atom proved to be sufficient for exclusive autonomous disrotary motion of two appended rotor moieties. Isomerization around the two double bonds enables both rotors to move in the same direction with respect to their surroundings - like wheels on an axle - demonstrating that autonomous unidirectional rotary motion can be achieved in a symmetric system.

Originele taal-2	English
Pagina's (van-tot)	890 - 896
Aantal pagina's	7
Tijdschrift	Nature Chemistry
Volume	7
Nummer van het tijdschrift	11
DOI's	https://doi.org/10.1038/nchem.2362
Status	Published - 12 okt. 2015
Extern gepubliceerd	Ja

Keywords

unidirectionele draaibeweging
achirale moleculaire motoren

Toegang tot document

10.1038/nchem.2362

7 Article

Third-Generation Light-Driven Symmetric Molecular Motors
Kistemaker, J. C. M., Štacko, P., Roke, D., Wolters, A. T., Heideman, H., Chang, M.-C., Van der Meulen, P., Visser, J., Otten, E. & Feringa, B. L., 19 jul. 2017, In: Journal of the American Chemical Society. 139, 28, blz. 9650 - 9661 12 blz.
Onderzoeksoutput: Article › Academic › peer review

Open Access
From chaos to order: Chain-length dependence of the free energy of formation of meso-tetraalkylporphyrin self-assembled monolayer polymorphs
Reimers, J. R., Panduwinata, D., Visser, J., Chin, Y., Tang, C., Goerigk, L., Ford, M. J., Baker, M., Sum, T.-J., Coenen, M. J. J., Hendriksen, B. L. M., Elemans, J. A. A. W., Hush, N. S. & Crossley, M. J., 5 jan. 2016, In: Journal of Physical Chemistry C. 120, 3, blz. 1739 - 1748 10 blz.
Onderzoeksoutput: Article › Academic › peer review

Open Access
A priori calculations of the free energy of formation from solution of polymorphic self-Assembled monolayers
Reimers, J. R., Panduwinata, D., Visser, J., Tang, C., Goerigk, L., Ford, M. J., Sintic, M., Sum, T.-J., Coenen, M. J. J., Hendriksen, B. L. M., Elemans, J. A. A. W., Hush, N. S. & Crossley, M. J., 28 okt. 2015, In: Proceedings of the National Academy of Sciences. 112, 45, blz. E6101 - E6110 10 blz.
Onderzoeksoutput: Article › Academic › peer review

Open Access

Citeer dit

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title = "Unidirectional rotary motion in achiral molecular motors",

abstract = "Control of the direction of motion is an essential feature of biological rotary motors and results from the intrinsic chirality of the amino acids from which the motors are made. In synthetic autonomous light-driven rotary motors, point chirality is transferred to helical chirality, and this governs their unidirectional rotation. However, achieving directional rotary motion in an achiral molecular system in an autonomous fashion remains a fundamental challenge. Here, we report an achiral molecular motor in which the presence of a pseudo-asymmetric carbon atom proved to be sufficient for exclusive autonomous disrotary motion of two appended rotor moieties. Isomerization around the two double bonds enables both rotors to move in the same direction with respect to their surroundings - like wheels on an axle - demonstrating that autonomous unidirectional rotary motion can be achieved in a symmetric system.",

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N2 - Control of the direction of motion is an essential feature of biological rotary motors and results from the intrinsic chirality of the amino acids from which the motors are made. In synthetic autonomous light-driven rotary motors, point chirality is transferred to helical chirality, and this governs their unidirectional rotation. However, achieving directional rotary motion in an achiral molecular system in an autonomous fashion remains a fundamental challenge. Here, we report an achiral molecular motor in which the presence of a pseudo-asymmetric carbon atom proved to be sufficient for exclusive autonomous disrotary motion of two appended rotor moieties. Isomerization around the two double bonds enables both rotors to move in the same direction with respect to their surroundings - like wheels on an axle - demonstrating that autonomous unidirectional rotary motion can be achieved in a symmetric system.

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IS - 11

ER -

Unidirectional rotary motion in achiral molecular motors

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Keywords

Toegang tot document

Vingerafdruk

Onderzoekersoutput

Third-Generation Light-Driven Symmetric Molecular Motors

From chaos to order: Chain-length dependence of the free energy of formation of meso-tetraalkylporphyrin self-assembled monolayer polymorphs

A priori calculations of the free energy of formation from solution of polymorphic self-Assembled monolayers

Citeer dit