The neglected puzzle of dementia in people with severe/profound intellectual disabilities: A systematic literature review of observable symptoms

Maureen B G Wissing; Aurora M Ulgiati; Johannes S M Hobbelen; Peter P De Deyn; Aly Waninge; Alain D Dekker

doi:10.1111/jar.12920

The neglected puzzle of dementia in people with severe/profound intellectual disabilities: A systematic literature review of observable symptoms

Maureen B G Wissing, Aurora M Ulgiati, Johannes S M Hobbelen, Peter P De Deyn, Aly Waninge, Alain D Dekker

Onderzoeksoutput: Review article › peer review

Samenvatting

BACKGROUND: Dementia is increasingly prevalent in people with severe/profound intellectual disabilities. However, early detection and diagnosis of dementia is complex in this population. This study aimed to identify observable dementia symptoms in adults with severe/profound intellectual disabilities in available literature.

METHOD: A systematic literature search was conducted in PubMed, PsycINFO and Web of Science with an exhaustive search string using a combination of search terms for severe/profound intellectual disabilities and dementia/ageing.

RESULTS: Eleven studies met inclusion criteria. Cognitive decline, behavioural and psychological alterations, decline in activities of daily living as well as neurological and physical changes were found.

CONCLUSIONS: Only a very limited number of studies reported symptoms ascribed to dementia in adults with severe/profound intellectual disabilities. Given the complexity of signalling and diagnosing dementia, dedicated studies are required to unravel the natural history of dementia in this population.

Originele taal-2	English
Pagina's (van-tot)	24-45
Aantal pagina's	22
Tijdschrift	Mental Handicap Research
Volume	35
Nummer van het tijdschrift	1
Vroegere onlinedatum	4 jul. 2021
DOI's	https://doi.org/10.1111/jar.12920
Status	Published - jan. 2022

Duurzame ontwikkelingsdoelstellingen van de VN

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SDG 03 – Goede gezondheid en welzijn

Keywords

dementie
syndroom van down
ouder worden

Research Focus Areas Hanze University of Applied Sciences

Healthy Ageing

Research Focus Areas Research Centre or Centre of Expertise

Kwetsbaarheid en passende zorg

Publinova thema's

Overig
Gezondheid

Toegang tot document

10.1111/jar.12920Licentie: CC BY

Citeer dit

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title = "The neglected puzzle of dementia in people with severe/profound intellectual disabilities: A systematic literature review of observable symptoms",

abstract = "BACKGROUND: Dementia is increasingly prevalent in people with severe/profound intellectual disabilities. However, early detection and diagnosis of dementia is complex in this population. This study aimed to identify observable dementia symptoms in adults with severe/profound intellectual disabilities in available literature.METHOD: A systematic literature search was conducted in PubMed, PsycINFO and Web of Science with an exhaustive search string using a combination of search terms for severe/profound intellectual disabilities and dementia/ageing.RESULTS: Eleven studies met inclusion criteria. Cognitive decline, behavioural and psychological alterations, decline in activities of daily living as well as neurological and physical changes were found.CONCLUSIONS: Only a very limited number of studies reported symptoms ascribed to dementia in adults with severe/profound intellectual disabilities. Given the complexity of signalling and diagnosing dementia, dedicated studies are required to unravel the natural history of dementia in this population.",

keywords = "dementia, down syndrome, ageing, dementie, syndroom van down, ouder worden",

author = "Wissing, \{Maureen B G\} and Ulgiati, \{Aurora M\} and Hobbelen, \{Johannes S M\} and \{De Deyn\}, \{Peter P\} and Aly Waninge and Dekker, \{Alain D\}",

note = "{\textcopyright} 2021 The Authors. Journal of Applied Research in Intellectual Disabilities published by John Wiley \& Sons Ltd.",

year = "2022",

month = jan,

doi = "10.1111/jar.12920",

language = "English",

volume = "35",

pages = "24--45",

journal = "Mental Handicap Research",

issn = "1360-2322",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - The neglected puzzle of dementia in people with severe/profound intellectual disabilities

T2 - A systematic literature review of observable symptoms

AU - Wissing, Maureen B G

AU - Ulgiati, Aurora M

AU - Hobbelen, Johannes S M

AU - De Deyn, Peter P

AU - Waninge, Aly

AU - Dekker, Alain D

PY - 2022/1

Y1 - 2022/1

N2 - BACKGROUND: Dementia is increasingly prevalent in people with severe/profound intellectual disabilities. However, early detection and diagnosis of dementia is complex in this population. This study aimed to identify observable dementia symptoms in adults with severe/profound intellectual disabilities in available literature.METHOD: A systematic literature search was conducted in PubMed, PsycINFO and Web of Science with an exhaustive search string using a combination of search terms for severe/profound intellectual disabilities and dementia/ageing.RESULTS: Eleven studies met inclusion criteria. Cognitive decline, behavioural and psychological alterations, decline in activities of daily living as well as neurological and physical changes were found.CONCLUSIONS: Only a very limited number of studies reported symptoms ascribed to dementia in adults with severe/profound intellectual disabilities. Given the complexity of signalling and diagnosing dementia, dedicated studies are required to unravel the natural history of dementia in this population.

AB - BACKGROUND: Dementia is increasingly prevalent in people with severe/profound intellectual disabilities. However, early detection and diagnosis of dementia is complex in this population. This study aimed to identify observable dementia symptoms in adults with severe/profound intellectual disabilities in available literature.METHOD: A systematic literature search was conducted in PubMed, PsycINFO and Web of Science with an exhaustive search string using a combination of search terms for severe/profound intellectual disabilities and dementia/ageing.RESULTS: Eleven studies met inclusion criteria. Cognitive decline, behavioural and psychological alterations, decline in activities of daily living as well as neurological and physical changes were found.CONCLUSIONS: Only a very limited number of studies reported symptoms ascribed to dementia in adults with severe/profound intellectual disabilities. Given the complexity of signalling and diagnosing dementia, dedicated studies are required to unravel the natural history of dementia in this population.

KW - dementia

KW - down syndrome

KW - ageing

KW - dementie

KW - syndroom van down

KW - ouder worden

U2 - 10.1111/jar.12920

DO - 10.1111/jar.12920

M3 - Review article

C2 - 34219327

SN - 1360-2322

VL - 35

SP - 24

EP - 45

JO - Mental Handicap Research

JF - Mental Handicap Research

IS - 1

ER -

The neglected puzzle of dementia in people with severe/profound intellectual disabilities: A systematic literature review of observable symptoms

Samenvatting

Duurzame ontwikkelingsdoelstellingen van de VN

Keywords

Research Focus Areas Hanze University of Applied Sciences

Research Focus Areas Research Centre or Centre of Expertise

Publinova thema's

Toegang tot document

Vingerafdruk

Citeer dit