The neglected puzzle of dementia in people with severe/profound intellectual disabilities: A systematic literature review of observable symptoms

Maureen B G Wissing, Aurora M Ulgiati, Johannes S M Hobbelen, Peter P De Deyn, Aly Waninge, Alain D Dekker

Onderzoeksoutput: Review articleAcademicpeer review

Samenvatting

BACKGROUND: Dementia is increasingly prevalent in people with severe/profound intellectual disabilities. However, early detection and diagnosis of dementia is complex in this population. This study aimed to identify observable dementia symptoms in adults with severe/profound intellectual disabilities in available literature.

METHOD: A systematic literature search was conducted in PubMed, PsycINFO and Web of Science with an exhaustive search string using a combination of search terms for severe/profound intellectual disabilities and dementia/ageing.

RESULTS: Eleven studies met inclusion criteria. Cognitive decline, behavioural and psychological alterations, decline in activities of daily living as well as neurological and physical changes were found.

CONCLUSIONS: Only a very limited number of studies reported symptoms ascribed to dementia in adults with severe/profound intellectual disabilities. Given the complexity of signalling and diagnosing dementia, dedicated studies are required to unravel the natural history of dementia in this population.

Originele taal-2English
Pagina's (van-tot)24-45
Aantal pagina's22
TijdschriftMental Handicap Research
Volume35
Nummer van het tijdschrift1
Vroegere onlinedatum4 jul. 2021
DOI's
StatusPublished - jan. 2022

Keywords

  • dementie
  • syndroom van down
  • ouder worden

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