Keyphrases
4-aminobenzoic Acid
57%
6-Aminopenicillanic Acid
14%
Acid-base Mechanism
14%
Acyl-coenzyme A
71%
Acylation
100%
Ampicillin
28%
Benzoic Acid
42%
Binding Experiment
14%
D 2O
14%
Deacylation
100%
Deuterium Isotope Effect
14%
Flow Experiment
14%
Fractionation Factor
14%
General Acid
14%
Glycerol
14%
High Affinity
14%
High Viscosity
14%
Hydrolysis
57%
Inverse Isotope Effect
28%
Isotope Effect
14%
Kcat
28%
Kinetic Aspects
14%
Kinetic Constants
14%
Kinetic Isotope Effect
14%
Lactams
14%
Mechanistic Aspects
14%
Molar Fraction
14%
Nitro
100%
Nucleophile
42%
Penicillin
14%
Penicillin Acylase
100%
Penicillin G
14%
Proton
14%
Proton Inventory
14%
Rate Measurement
14%
Rate-limiting Step
28%
Semi-synthetic
14%
Steady State
14%
Stopped Flow
14%
Transition State
14%
Via Formation
14%
β-lactam Antibiotics
100%
Chemistry
6-Aminopenicillanic Acid
14%
Acylation
100%
Ampicillin
28%
Base
14%
Benzoic Acid
100%
Beta Lactam Antibiotic Agent
100%
Deacylation
100%
Enzymatic Hydrolysis
57%
formation
42%
Kcat
28%
Kinetic Isotope Effect
28%
Lactam
14%
Nucleophile
42%
Penicillin
100%
Transition State
14%
Pharmacology, Toxicology and Pharmaceutical Science
6 Aminopenicillanic Acid
25%
Amidase
100%
Aminobenzoic Acid
100%
Ampicillin
50%
Base
25%
Benzoic Acid
75%
Beta Lactam Antibiotic
100%
Deuterium
25%
Lactam
25%
Nucleophile
75%
Penicillin Derivative
100%
Penicillin G
25%
Biochemistry, Genetics and Molecular Biology