Samenvatting
Small RNAs are important regulators of genome function, yet their prediction in genomes is still a major computational challenge. Statistical analyses of pre-miRNA sequences indicated that their 2D structure tends to have a minimal free energy (MFE) significantly lower than MFE values of equivalently randomized sequences with the same nucleotide composition, in contrast to other classes of non-coding RNA. The computation of many MFEs is, however, too intensive to allow for genome-wide screenings.
| Originele taal-2 | English |
|---|---|
| Aantal pagina's | 10 |
| Tijdschrift | BMC Research Notes |
| Status | Published - 13 jan. 2014 |
Duurzame ontwikkelingsdoelstellingen van de VN
Deze output draagt bij aan de volgende duurzame ontwikkelingsdoelstelling(en)
-
SDG 07 – Betaalbare en schone energie -
SDG 09 – Industrie, innovatie en infrastructuur
Keywords
- moleculaire technieken
Research Focus Areas Hanze University of Applied Sciences
- Energie
Research Focus Areas Research Centre or Centre of Expertise
- Hernieuwbare brandstoffen en duurzame gassen
Publinova thema's
- Techniek
Vingerafdruk
Duik in de onderzoeksthema's van 'Fast selection of miRNA candidates based on large-scale pre-computed MFE sets of randomized sequences.'. Samen vormen ze een unieke vingerafdruk.Citeer dit
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver