Does muscle mass measured with Computed Tomography analysis differ in patients with different types of cancer? Results from the BODY‑CONVERT Study Group

Martine Sealy, Jona Van den Broeck, Carola Brussaard, Aldo Scafoglieri, Harriët Jager-Wittenaar

Onderzoeksoutput: AbstractAcademic

Samenvatting

Rationale: Patients with cancer of the upper gastrointestinal tract or lung are more likely to present with malnutrition at diagnosis than, for instance, patients with melanoma. Low muscle mass is an indicator of malnutrition and can be determined by computed tomography (CT) analysis of the skeletal muscle index (SMI) at the 3rd lumbar vertebra (L3) level. However, CT images at L3 are not always available. At each vertebra level, we determined if type of cancer, i.e., head and neck cancer (HNC), oesophageal cancer (OC) or lung cancer (LC) vs. melanoma (ME) was associated with lower SMI. Methods: CT images from adult patients with HNC, OC, LC or ME were included and analyzed. Scans were performed in the patient’s initial staging after diagnosis. MIM software version 7.0.1 was used to contour the muscle areas for all vertebra levels. Skeletal muscle area was corrected for stature to calculate SMI (cm2/m2). We tested for the association of HNC, OC, or LC diagnosis vs ME with SMI by univariate and multivariate linear regression analyses. In the multivariate analyses, age (years), sex, and body mass index (BMI; kg/m2) were included. Betas (B;95%CI) were calculated and statistical significance was set at p
Originele taal-2English
Pagina'sS555
Aantal pagina's22
DOI's
StatusPublished - 1 dec. 2021
EvenementESPEN2021 - online
Duur: 9 sep. 202114 sep. 2021
Congresnummer: 52
http://www.espencongress.com

Conference

ConferenceESPEN2021
Periode9/09/2114/09/21
Internet adres

Keywords

  • lichaamssamenstelling
  • spiermassa
  • CT-spieranalyse
  • oncologie

Vingerafdruk

Duik in de onderzoeksthema's van 'Does muscle mass measured with Computed Tomography analysis differ in patients with different types of cancer? Results from the BODY‑CONVERT Study Group'. Samen vormen ze een unieke vingerafdruk.

Citeer dit