Autoantibody profiles in systemic sclerosis: a comparison of diagnostic tests

Wynand Alkema; Hans J P M Koenen; Brigit E. Kersten; Charlotte Kaffa; Jaqueline W Nannenberg-Koops; Jan G. M. C.  Damoiseux

Autoantibody profiles in systemic sclerosis: a comparison of diagnostic tests

Wynand Alkema, Hans J P M Koenen, Brigit E. Kersten, Charlotte Kaffa, Jaqueline W Nannenberg-Koops, Jan G. M. C. Damoiseux

Radboudumc

Onderzoeksoutput: Article › Academic › peer review

Samenvatting

Onderzoek naar de profilering van antilichamen in de prognose en classificatie van systemische sclerose. Het doel van het onderzoek was om commercieel beschikbare diagnostische assays voor de detectie van SSc-geassocieerde autoantilichamen te vergelijken. Daarnaast werder onderzoek gedaan naar de coëxistentie van meerdere SSc-geassocieerde autoantilichamen bij patiënten.

Originele taal-2	English
Pagina's (van-tot)	148-155
Aantal pagina's	7
Tijdschrift	Autoimmunity
Volume	54
Nummer van het tijdschrift	3
Status	Published - 5 apr. 2021

Keywords

antistoffen
systemische sclerose

Toegang tot document

https://www.tandfonline.com/doi/figure/10.1080/08916934.2021.1907842?scroll=top&needAccess=true

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Open Access
Bestand

Data-onderzoek legt patronen bloot in het belang van gezondheid
Alkema, W.
7/11/23
1 item van Media-aandacht
Pers / media: Expert Comment
'Productontwikkelaars moeten zich verdiepen in de mogelijkheden van Artificial intelligence'
Alkema, W.
17/09/23
1 item van Media-aandacht
Pers / media: Expert Comment

Citeer dit

@article{3a8cc3403aed42c5b4b330e40376a074,

title = "Autoantibody profiles in systemic sclerosis: a comparison of diagnostic tests",

abstract = "Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays. However, standardization in autoimmune serology is lacking, which may have a negative impact on the added value of autoantibodies in diagnosis and prognosis of SSc. In this paper we describe the comparison of commercially available diagnostic assays for the detection of SSc-associated autoantibodies and explored the coexistence of multiple SSc-associated autoantibodies within patients.",

keywords = "antistoffen, systemische sclerose, systemic sclerosis, diagnostic assays, antibodies",

author = "Wynand Alkema and Koenen, \{Hans J P M\} and Kersten, \{Brigit E.\} and Charlotte Kaffa and Nannenberg-Koops, \{Jaqueline W\} and Damoiseux, \{Jan G. M. C.\}",

year = "2021",

month = apr,

day = "5",

language = "English",

volume = "54",

pages = "148--155",

journal = "Autoimmunity",

issn = "1607-842X",

publisher = "Taylor and Francis Ltd.",

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}

TY - JOUR

T1 - Autoantibody profiles in systemic sclerosis

T2 - a comparison of diagnostic tests

AU - Alkema, Wynand

AU - Koenen, Hans J P M

AU - Kersten, Brigit E.

AU - Kaffa, Charlotte

AU - Nannenberg-Koops, Jaqueline W

AU - Damoiseux, Jan G. M. C.

PY - 2021/4/5

Y1 - 2021/4/5

N2 - Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays. However, standardization in autoimmune serology is lacking, which may have a negative impact on the added value of autoantibodies in diagnosis and prognosis of SSc. In this paper we describe the comparison of commercially available diagnostic assays for the detection of SSc-associated autoantibodies and explored the coexistence of multiple SSc-associated autoantibodies within patients.

AB - Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays. However, standardization in autoimmune serology is lacking, which may have a negative impact on the added value of autoantibodies in diagnosis and prognosis of SSc. In this paper we describe the comparison of commercially available diagnostic assays for the detection of SSc-associated autoantibodies and explored the coexistence of multiple SSc-associated autoantibodies within patients.

KW - antistoffen

KW - systemische sclerose

KW - systemic sclerosis

KW - diagnostic assays

KW - antibodies

M3 - Article

SN - 1607-842X

VL - 54

SP - 148

EP - 155

JO - Autoimmunity

JF - Autoimmunity

IS - 3

ER -

Autoantibody profiles in systemic sclerosis: a comparison of diagnostic tests

Samenvatting

Keywords

Toegang tot document

Vingerafdruk

Onderzoekersoutput

Nailfold capillaroscopy and candidate-biomarker levels in systemic sclerosis-associated pulmonary hypertension: A cross-sectional study

The 3Ranker: An AI-based Algorithm for Finding Non-animal Alternative Methods

Blood-Based Immune Profiling Combined with Machine Learning Discriminates Psoriatic Arthritis from Psoriasis Patients

Pers/Media

Data-onderzoek legt patronen bloot in het belang van gezondheid

'Productontwikkelaars moeten zich verdiepen in de mogelijkheden van Artificial intelligence'

Citeer dit