Autoantibody profiles in systemic sclerosis: a comparison of diagnostic tests

Wynand Alkema; Hans J P M Koenen; Brigit E. Kersten; Charlotte Kaffa; Jaqueline W Nannenberg-Koops; Jan G. M. C.  Damoiseux

Autoantibody profiles in systemic sclerosis: a comparison of diagnostic tests

Wynand Alkema, Hans J P M Koenen, Brigit E. Kersten, Charlotte Kaffa, Jaqueline W Nannenberg-Koops, Jan G. M. C. Damoiseux

Data Science for Life Science & Health

Radboud UMC

Onderzoeksoutput: Article › Academic › peer review

Samenvatting

Onderzoek naar de profilering van antilichamen in de prognose en classificatie van systemische sclerose. Het doel van het onderzoek was om commercieel beschikbare diagnostische assays voor de detectie van SSc-geassocieerde autoantilichamen te vergelijken. Daarnaast werder onderzoek gedaan naar de coëxistentie van meerdere SSc-geassocieerde autoantilichamen bij patiënten.

Originele taal-2	English
Pagina's (van-tot)	148-155
Aantal pagina's	7
Tijdschrift	Autoimmunity
Volume	54
Nummer van het tijdschrift	3
Status	Published - 5 apr. 2021

Keywords

antistoffen
systemische sclerose

Toegang tot document

https://www.tandfonline.com/doi/figure/10.1080/08916934.2021.1907842?scroll=top&needAccess=true

1 Article
1 Website

Blood-Based Immune Profiling Combined with Machine Learning Discriminates Psoriatic Arthritis from Psoriasis Patients
Alkema, W., He, X., Kaffa, C., Joosten, I., Smeets, R. L., Koenen, H. J. P. M., Mulder, M. L. M., van den Reek, J. M. P. A., Urbano, P. C. M., Wang, X., van Cranenbroek, B., van Rijssen, E., Van Den Hoogen, F. H. J., de Jong, E. M. G. . J. & Wenink, M. H., 12 okt. 2021, In: International Journal of Molecular Sciences. 22, 10 blz., 10990.
Onderzoeksoutput: Article › Academic › peer review

Open Access
Bestand
Het recept voor een succesvol data science project
Alkema, W., 18 dec. 2020
Onderzoeksoutput: Website › Professional

Open Access

Data-onderzoek legt patronen bloot in het belang van gezondheid
Wynand Alkema
7/11/23
1 item van Media-aandacht
Pers / media: Expert Comment
'Productontwikkelaars moeten zich verdiepen in de mogelijkheden van Artificial intelligence'
Wynand Alkema
17/09/23
1 item van Media-aandacht
Pers / media: Expert Comment

Citeer dit

@article{3a8cc3403aed42c5b4b330e40376a074,

title = "Autoantibody profiles in systemic sclerosis: a comparison of diagnostic tests",

abstract = "Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays. However, standardization in autoimmune serology is lacking, which may have a negative impact on the added value of autoantibodies in diagnosis and prognosis of SSc. In this paper we describe the comparison of commercially available diagnostic assays for the detection of SSc-associated autoantibodies and explored the coexistence of multiple SSc-associated autoantibodies within patients.",

keywords = "antistoffen, systemische sclerose, systemic sclerosis, diagnostic assays, antibodies",

author = "Wynand Alkema and Koenen, {Hans J P M} and Kersten, {Brigit E.} and Charlotte Kaffa and Nannenberg-Koops, {Jaqueline W} and Damoiseux, {Jan G. M. C.}",

year = "2021",

month = apr,

day = "5",

language = "English",

volume = "54",

pages = "148--155",

journal = "Autoimmunity",

issn = "0891-6934",

publisher = "Taylor & Francis",

number = "3",

}

TY - JOUR

T1 - Autoantibody profiles in systemic sclerosis

T2 - a comparison of diagnostic tests

AU - Alkema, Wynand

AU - Koenen, Hans J P M

AU - Kersten, Brigit E.

AU - Kaffa, Charlotte

AU - Nannenberg-Koops, Jaqueline W

AU - Damoiseux, Jan G. M. C.

PY - 2021/4/5

Y1 - 2021/4/5

N2 - Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays. However, standardization in autoimmune serology is lacking, which may have a negative impact on the added value of autoantibodies in diagnosis and prognosis of SSc. In this paper we describe the comparison of commercially available diagnostic assays for the detection of SSc-associated autoantibodies and explored the coexistence of multiple SSc-associated autoantibodies within patients.

AB - Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays. However, standardization in autoimmune serology is lacking, which may have a negative impact on the added value of autoantibodies in diagnosis and prognosis of SSc. In this paper we describe the comparison of commercially available diagnostic assays for the detection of SSc-associated autoantibodies and explored the coexistence of multiple SSc-associated autoantibodies within patients.

KW - antistoffen

KW - systemische sclerose

KW - systemic sclerosis

KW - diagnostic assays

KW - antibodies

M3 - Article

SN - 0891-6934

VL - 54

SP - 148

EP - 155

JO - Autoimmunity

JF - Autoimmunity

IS - 3

ER -

Autoantibody profiles in systemic sclerosis: a comparison of diagnostic tests

Samenvatting

Keywords

Toegang tot document

Vingerafdruk

Onderzoekersoutput

Blood-Based Immune Profiling Combined with Machine Learning Discriminates Psoriatic Arthritis from Psoriasis Patients

Het recept voor een succesvol data science project

Pers/Media

Data-onderzoek legt patronen bloot in het belang van gezondheid

'Productontwikkelaars moeten zich verdiepen in de mogelijkheden van Artificial intelligence'

Citeer dit