Allosterically driven multicomponent assembly

Pall Thordarson, Ruud G.E. Coumans, Johannes A.A.W. Elemans, Johan Visser, Paul J. Thomassen, Alan E. Rowan, Roeland J.M. Nolte

Onderzoeksoutput: ArticleAcademicpeer review


Bound to cooperate: Binding of dimethylviologen in the cavity of a Zn porphyrin host dramatically increases the affinity of the host for N-donating ligands and vice versa (see scheme). These positive heterotropic allosteric effects are exploited to direct complex equilibrium mixtures towards a single self-assembled species. This allosteric magnification was used to obtain a pentameric sandwich architecture from a complex mixture of components.
Originele taal-2English
Pagina's (van-tot)4755-4759
Aantal pagina's5
TijdschriftAngewandte Chemie International Edition
Nummer van het tijdschrift36
StatusPublished - 7 sep. 2004
Extern gepubliceerdJa


  • allosteric effects
  • dimethylviologen
  • chemical compounds
  • multicomponents


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