TY - JOUR
T1 - A review on static splinting therapy to prevent burn scar contracture:
T2 - do clinical and experimental data warrant its clinical application?
AU - Schouten, H.J.
AU - Nieuwenhuis, M.K.
AU - van Zuijlen, P.P.M.
N1 - Copyright © 2011 Elsevier Ltd and ISBI. All rights reserved.
PY - 2012/2/1
Y1 - 2012/2/1
N2 - BACKGROUND: Static splinting therapy is widely considered an essential part in burn rehabilitation to prevent scar contractures in the early phase of wound healing. However, scar contractures are still a common complication. In this article we review the information concerning the incidence of scar contracture, the effectiveness of static splinting therapy in preventing scar contractures, and specifically focus on the - possible - working mechanism of static-splinting, i.e. mechanical load, at the cellular and molecular level of the healing burn wound.METHOD: A literature search was done including Pubmed, Cochrane library, CINAHL and PEDRO.RESULTS: Incidence of scar contracture in patients with burns varied from 5% to 40%. No strong evidence for the effectiveness of static splinting therapy in preventing scar contracture was found, whereas in vitro and animal studies demonstrated that mechanical tension will stimulate the myofibroblast activity, resulting in the synthesis of new extracellular matrix and the maintenance of their contractile activity.CONCLUSION: The effect of mechanical tension on the wound healing process suggests that static splinting therapy may counteract its own purpose. This review stresses the need for randomised controlled clinical trials to establish if static splinting to prevent contractures is a well-considered intervention or just wishful thinking.
AB - BACKGROUND: Static splinting therapy is widely considered an essential part in burn rehabilitation to prevent scar contractures in the early phase of wound healing. However, scar contractures are still a common complication. In this article we review the information concerning the incidence of scar contracture, the effectiveness of static splinting therapy in preventing scar contractures, and specifically focus on the - possible - working mechanism of static-splinting, i.e. mechanical load, at the cellular and molecular level of the healing burn wound.METHOD: A literature search was done including Pubmed, Cochrane library, CINAHL and PEDRO.RESULTS: Incidence of scar contracture in patients with burns varied from 5% to 40%. No strong evidence for the effectiveness of static splinting therapy in preventing scar contracture was found, whereas in vitro and animal studies demonstrated that mechanical tension will stimulate the myofibroblast activity, resulting in the synthesis of new extracellular matrix and the maintenance of their contractile activity.CONCLUSION: The effect of mechanical tension on the wound healing process suggests that static splinting therapy may counteract its own purpose. This review stresses the need for randomised controlled clinical trials to establish if static splinting to prevent contractures is a well-considered intervention or just wishful thinking.
KW - burns/complications
KW - cicatrix, hypertrophic/complications
KW - contracture/epidemiology
KW - humans
KW - incidence
KW - Netherlands/epidemiology
KW - splints
KW - stress, mechanical
KW - wound healing/physiology
KW - brandwonden/complicaties
KW - mensen
KW - incidentie
KW - Nederland/epidemiologie
KW - spalken
KW - stress/mechanisch
KW - wondheling/fysiologie
KW - contractuur/epidemiologie
KW - litteken, hypertrofisch/complicaties
U2 - 10.1016/j.burns.2011.06.003
DO - 10.1016/j.burns.2011.06.003
M3 - Review article
C2 - 21831527
SN - 0305-4179
VL - 38
SP - 19
EP - 25
JO - Burns : journal of the International Society for Burn Injuries
JF - Burns : journal of the International Society for Burn Injuries
IS - 1
ER -