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Erik Keller (11-03-1970) obtained his PhD in Organic chemistry under the supervision of Prof. dr. Ben L. Feringa in 1998 working on “Catalytic enantioselective conjugate addition reactions: with a focus on water”. Afterwards he started his career in R&D in organic chemistry at Syncom bv where he worked in different positions and was responsible for various development programs ranging from early stage medicinal chemistry to scale up and development and synthesis of complex (chiral) building blocks, novell chemical entities and stable isotope labeled compounds. Later he joined Lab Ofichem as head of R&D, where he was responsible for the development and implementation of production methods for novel active pharmaceutical ingredients.
Early 2020 joined the Kenniscentrum Biobased Economy where he ao is working on the upcycling of polyhydroxyalkanoate monomers and oligomers for pharmaceutical, (functional) food and polymer recycling. ‘
His main interests are on the development of sustainable green life science implementations.
1,3-Dipolar cycloadditions to 5-methoxy-2(5H)-furanone
Erik Keller, Ben de Lange, Minze T. Rispens, Ben L. Feringa, Tetrahedron 1993, 49, 8899.
Asymmetric 1,3-dipolar cycloadditions to 5-(R)-menthyloxy-2(5H)-furanone
Minze T. Rispens, Erik Keller, Ben de Lange, Robert W.J. Zijlstra, Ben L. Feringa, Tetrahedron Asymmetry 1994, 5, 607.
Synthesis of (11C)methyl magnesium iodide and its application to the introduction of(11C)-N-tert-butyl groups and (11C)-sec-alcohols
Philip H. Elsinga, Erik Keller, Tjibbe J. de Groot, Gerben M. Visser, Willem Vaalburg, Applied radiation and isotopes 1995, 46, 227.
Ytterbium triflate catalyzed Michael additions of b-ketoesters in water
Erik Keller, Ben L. Feringa, Tetrahedron Letters 1996, 7, 1879.
Lewis-acid catalysis of carbon carbon bond forming reactions in water
Jan B.N.F. Engberts, Ben L. Feringa, Erik Keller, Sijbren Otto, Recueil des TravauxChimiques des Pays-Bas 1996, 115, 457.
Highly efficient ytterbium triflate catalyzed Michael additions of a-nitroesters in water
Erik Keller, Ben L. Feringa, Synlett 1997, 842.
Catalytic enantioselective Michael addition reactions of a-nitroesters to a,b-unsaturated ketones
Erik Keller, Nora Veldman, Anthony L. Spek, Ben L, Feringa, Tetrahedron Asymmetry 1997, 8, 3403.
Unexpected enhancement of enantioselectivity in copper (II) catalyzed conjugate addition of diethylzinc to cyclic enones with novel TADDOL phosphorus amidite ligands
Erik Keller, Jochen Maurer, Robert Naasz, Thomas Schader, Auke Meetsma, Ben L. Feringa Tetrahedron Asymmetry 1998,9, 2094
(±)-6,6'-Dinitro-1,1'-binaphthyl 2,2'-diacetate
Auke Meetsma, Erik Keller, Ben L.Feringa, Acta Cryst. 1999, C55, 450.
Catalytic Enantioselective Annulations via 1,4-Addition-Aldol Cyclization of Functionalized Organozinc Reagents
Robert Naasz, Leggy A. Arnold, Mauro Pineschi, Erik Keller, Ben L. Feringa, J. Am. Chem. Soc. 1999, 121, 1104.
Biotransformation-mediated synthesis of (1S)-1-(2,6-dichloro-3-fluorophenyl)ethanol in enantiomerically pure form
Carlos A. Martinez, Erik Keller, Renzo Meijer, Gerard Metselaar, Gerlof Kruithof, Curtis Moore and Pei-Pei Kung Tetrahedron Asymmetry 2010, 21, 2408.
(1,4)-Benzodiazepines vasopressin V2 receptor antagonisys
Leen Thielemans. Maarten van Geffen, Ann Meulemans, Marina Cools, Erik Keller, Karel Lavrijsen GB 1013708.1.
Process to extract and purify delta-9-tetrahydrocannabinol
Changoer, L.; Loo C.H.M. van der; Keller, E. WO 2016/179247 A1.
Rapid chemoenzymatic route to glutamate transporter inhibitor L-TFB-TBOA and related amino acids
Haigen Fu, Sabry H. H. Younes, Mohammad Saifuddin, Pieter G. Tepper, Jielin Zhang, Erik Keller, André Heeres, Wiktor Szymanski and Gerrit J. Poelarend Org. Biomol. Chem., 2017,15, 2341-2344.
Methods for providing highly pure palmitoylethanolamide (PEA), pure PEA preparationsm and uses thereof
Dabous, S.J.; Keller E. WO2019066644.
Onderzoeksoutput: Poster › Academic
Onderzoeksoutput: Article › Academic › peer review
Onderzoeksoutput: Article › Professional
Onderzoeksoutput: Patent › Professional
Onderzoeksoutput: Patent › Academic
André Heeres (Speaker) & Erik Keller (Speaker)
Activiteit: Invited talk
Erik Keller (Keynote speaker) & Corinne van Noordenne (Keynote speaker)
Activiteit: Invited talk
André Heeres (Speaker) & Erik Keller (Speaker)
Activiteit: Invited talk
Erik Keller (Speaker)
Activiteit: Oral presentation
Erik Keller (Speaker) & André Heeres (Speaker)
Activiteit: Oral presentation
11/02/21
1 Mediabijdrage
Pers / media: Expert Comment