Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition

Alina Kunnen, Judith Blaauw, Jasper J. van Doormaal, Maria G van Pampus, Cees van der Schans, Jan G Aarnoudse, Arie J van Winkelhoff, Frank Abbas

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with early-onset pre-eclampsia (<34 weeks).

METHODS: A case-control study was carried out on 17 early-onset pre-eclamptic women and 35 controls with uncomplicated pregnancies in a period of 3-28 months postpartum. All were Caucasians. Full-mouth periodontal examinations were performed to determine the periodontal condition. Subgingival-plaque samples were analysed by anaerobic culture techniques for the presence of seven bacterial periodontal pathogens. Potential confounders as age, smoking, educational level and body mass index were determined.

RESULTS: Severe periodontal disease was found in 82% of the pre-eclamptic and in 37% of the control group (p=0.009). After adjusting for age, smoking and educational level, the odds ratio was 7.9 (95% CI: 1.9-32.8). The periodontopathic microorganism Micromonas micros was more prevalent in the case group (p=0.040) while Campylobacter rectus was more prevalent in the control group (p=0.047).

CONCLUSION: These results indicate that Caucasian women with a recent history of early-onset pre-eclampsia have a worse periodontal condition, as compared with women with uncomplicated deliveries.

Original languageEnglish
Pages (from-to)202-207
JournalJournal of clinical periodontology
Volume34
Issue number3
DOIs
Publication statusPublished - Mar 2007

Keywords

  • adults
  • dental plaque
  • epidemiologic methods
  • females
  • gingival crevicular fluid
  • oral hygiene
  • periodontal diseases
  • pre-eclampsia
  • pregnancy

Cite this

Kunnen, Alina ; Blaauw, Judith ; van Doormaal, Jasper J. ; van Pampus, Maria G ; van der Schans, Cees ; Aarnoudse, Jan G ; van Winkelhoff, Arie J ; Abbas, Frank. / Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition. In: Journal of clinical periodontology. 2007 ; Vol. 34, No. 3. pp. 202-207.
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title = "Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition",
abstract = "OBJECTIVE: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with early-onset pre-eclampsia (<34 weeks).METHODS: A case-control study was carried out on 17 early-onset pre-eclamptic women and 35 controls with uncomplicated pregnancies in a period of 3-28 months postpartum. All were Caucasians. Full-mouth periodontal examinations were performed to determine the periodontal condition. Subgingival-plaque samples were analysed by anaerobic culture techniques for the presence of seven bacterial periodontal pathogens. Potential confounders as age, smoking, educational level and body mass index were determined.RESULTS: Severe periodontal disease was found in 82{\%} of the pre-eclamptic and in 37{\%} of the control group (p=0.009). After adjusting for age, smoking and educational level, the odds ratio was 7.9 (95{\%} CI: 1.9-32.8). The periodontopathic microorganism Micromonas micros was more prevalent in the case group (p=0.040) while Campylobacter rectus was more prevalent in the control group (p=0.047).CONCLUSION: These results indicate that Caucasian women with a recent history of early-onset pre-eclampsia have a worse periodontal condition, as compared with women with uncomplicated deliveries.",
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author = "Alina Kunnen and Judith Blaauw and {van Doormaal}, {Jasper J.} and {van Pampus}, {Maria G} and {van der Schans}, Cees and Aarnoudse, {Jan G} and {van Winkelhoff}, {Arie J} and Frank Abbas",
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Kunnen, A, Blaauw, J, van Doormaal, JJ, van Pampus, MG, van der Schans, C, Aarnoudse, JG, van Winkelhoff, AJ & Abbas, F 2007, 'Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition' Journal of clinical periodontology, vol. 34, no. 3, pp. 202-207. https://doi.org/10.1111/j.1600-051X.2006.01036.x

Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition. / Kunnen, Alina; Blaauw, Judith; van Doormaal, Jasper J.; van Pampus, Maria G; van der Schans, Cees; Aarnoudse, Jan G; van Winkelhoff, Arie J; Abbas, Frank.

In: Journal of clinical periodontology, Vol. 34, No. 3, 03.2007, p. 202-207.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition

AU - Kunnen, Alina

AU - Blaauw, Judith

AU - van Doormaal, Jasper J.

AU - van Pampus, Maria G

AU - van der Schans, Cees

AU - Aarnoudse, Jan G

AU - van Winkelhoff, Arie J

AU - Abbas, Frank

PY - 2007/3

Y1 - 2007/3

N2 - OBJECTIVE: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with early-onset pre-eclampsia (<34 weeks).METHODS: A case-control study was carried out on 17 early-onset pre-eclamptic women and 35 controls with uncomplicated pregnancies in a period of 3-28 months postpartum. All were Caucasians. Full-mouth periodontal examinations were performed to determine the periodontal condition. Subgingival-plaque samples were analysed by anaerobic culture techniques for the presence of seven bacterial periodontal pathogens. Potential confounders as age, smoking, educational level and body mass index were determined.RESULTS: Severe periodontal disease was found in 82% of the pre-eclamptic and in 37% of the control group (p=0.009). After adjusting for age, smoking and educational level, the odds ratio was 7.9 (95% CI: 1.9-32.8). The periodontopathic microorganism Micromonas micros was more prevalent in the case group (p=0.040) while Campylobacter rectus was more prevalent in the control group (p=0.047).CONCLUSION: These results indicate that Caucasian women with a recent history of early-onset pre-eclampsia have a worse periodontal condition, as compared with women with uncomplicated deliveries.

AB - OBJECTIVE: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with early-onset pre-eclampsia (<34 weeks).METHODS: A case-control study was carried out on 17 early-onset pre-eclamptic women and 35 controls with uncomplicated pregnancies in a period of 3-28 months postpartum. All were Caucasians. Full-mouth periodontal examinations were performed to determine the periodontal condition. Subgingival-plaque samples were analysed by anaerobic culture techniques for the presence of seven bacterial periodontal pathogens. Potential confounders as age, smoking, educational level and body mass index were determined.RESULTS: Severe periodontal disease was found in 82% of the pre-eclamptic and in 37% of the control group (p=0.009). After adjusting for age, smoking and educational level, the odds ratio was 7.9 (95% CI: 1.9-32.8). The periodontopathic microorganism Micromonas micros was more prevalent in the case group (p=0.040) while Campylobacter rectus was more prevalent in the control group (p=0.047).CONCLUSION: These results indicate that Caucasian women with a recent history of early-onset pre-eclampsia have a worse periodontal condition, as compared with women with uncomplicated deliveries.

KW - adults

KW - dental plaque

KW - epidemiologic methods

KW - females

KW - gingival crevicular fluid

KW - oral hygiene

KW - periodontal diseases

KW - pre-eclampsia

KW - pregnancy

KW - volwassenen

KW - tandplak

KW - epidemologische methoden

KW - vrouwen

KW - gezondheidsstatus

KW - mondhygiëne

KW - paradontale ziekten

KW - pre-eclampsie

KW - zwangerschap

U2 - 10.1111/j.1600-051X.2006.01036.x

DO - 10.1111/j.1600-051X.2006.01036.x

M3 - Article

VL - 34

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EP - 207

JO - Journal of clinical periodontology

JF - Journal of clinical periodontology

SN - 0303-6979

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ER -