Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition

Alina Kunnen, Judith Blaauw, Jasper J. van Doormaal, Maria G van Pampus, Cees van der Schans, Jan G Aarnoudse, Arie J van Winkelhoff, Frank Abbas

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: Pre-eclampsia is a complication of pregnancy characterized by systemic vascular dysfunction and pathological changes in placental arteries. Growing evidence of chronic infection as an aetiological factor in vascular diseases prompted us to study maternal periodontal disease in subjects with early-onset pre-eclampsia (<34 weeks).

METHODS: A case-control study was carried out on 17 early-onset pre-eclamptic women and 35 controls with uncomplicated pregnancies in a period of 3-28 months postpartum. All were Caucasians. Full-mouth periodontal examinations were performed to determine the periodontal condition. Subgingival-plaque samples were analysed by anaerobic culture techniques for the presence of seven bacterial periodontal pathogens. Potential confounders as age, smoking, educational level and body mass index were determined.

RESULTS: Severe periodontal disease was found in 82% of the pre-eclamptic and in 37% of the control group (p=0.009). After adjusting for age, smoking and educational level, the odds ratio was 7.9 (95% CI: 1.9-32.8). The periodontopathic microorganism Micromonas micros was more prevalent in the case group (p=0.040) while Campylobacter rectus was more prevalent in the control group (p=0.047).

CONCLUSION: These results indicate that Caucasian women with a recent history of early-onset pre-eclampsia have a worse periodontal condition, as compared with women with uncomplicated deliveries.

Original languageEnglish
Pages (from-to)202-207
JournalJournal of clinical periodontology
Volume34
Issue number3
DOIs
Publication statusPublished - Mar 2007

Keywords

  • adults
  • dental plaque
  • epidemiologic methods
  • females
  • gingival crevicular fluid
  • oral hygiene
  • periodontal diseases
  • pre-eclampsia
  • pregnancy

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    Kunnen, A., Blaauw, J., van Doormaal, J. J., van Pampus, M. G., van der Schans, C., Aarnoudse, J. G., van Winkelhoff, A. J., & Abbas, F. (2007). Women with a recent history of early-onset pre-eclampsia have a worse periodontal condition. Journal of clinical periodontology, 34(3), 202-207. https://doi.org/10.1111/j.1600-051X.2006.01036.x