TKI sensitivity of ROS1+ lung cancer cell lines in 2D versus 3D culturing conditions

Christa Dijkhuizen; Patrick  Korthuis; Cristina Aguado; Silvia Garcia-Román; Andrés Aguilar-Hernández; Lyndsay Drayer; Margot De Looff; Fin Milder; Anke van den Berg; Anthonie van der Wekken

TKI sensitivity of ROS1+ lung cancer cell lines in 2D versus 3D culturing conditions

Christa Dijkhuizen (First author)
, Patrick Korthuis
, Cristina Aguado
, Silvia Garcia-Román
, Andrés Aguilar-Hernández
, Lyndsay Drayer
, Margot De Looff
, Fin Milder
, Anke van den Berg
, Anthonie van der Wekken

Biomolecules & Health

Dexeus University Hospital, Pangaea Oncology
Quirón Dexeus University Hospital, Dr Rosell Oncology Institute
University of Groningen, University Medical Center Groningen, Department of Pulmonology
University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology

Research output: Contribution to conference › Abstract › Academic

Original language	English
Number of pages	2
Publication status	Accepted/In press - 15 Jul 2025
Event	European Association for Cancer Research 2025: Goodbye Flat Biology - Essen, Germany Duration: 22 Sept 2025 → 25 Sept 2025

Conference

Conference	European Association for Cancer Research 2025
Abbreviated title	EACR2025
Country/Territory	Germany
City	Essen
Period	22/09/25 → 25/09/25

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 03 Good Health and Well-being

Keywords

ROS1
ROS1 inhibitors
patient derived cell lines
3D cell culture
2D cell culture

Research Focus Areas Hanze University of Applied Sciences * (mandatory by Hanze)

Healthy Ageing

Research Focus Areas Research Centre or Centre of Expertise * (mandatory by Hanze)

Medical Diagnostics & Point of Care Testing
Healthcare & Biotechnology

Publinova themes

Health

Cite this

@conference{68272a6467a0498db971ad5c7fc55b34,

title = "TKI sensitivity of ROS1+ lung cancer cell lines in 2D versus 3D culturing conditions",

keywords = "ROS1, ROS1-remmers, cellijnen afkomstig van pati{\"e}nten, 3D-celcultuur, 2D-celcultuur, ROS1, ROS1 inhibitors, patient derived cell lines, 3D cell culture, 2D cell culture",

author = "Christa Dijkhuizen and Patrick Korthuis and Cristina Aguado and Silvia Garcia-Rom{\'a}n and Andr{\'e}s Aguilar-Hern{\'a}ndez and Lyndsay Drayer and \{De Looff\}, Margot and Fin Milder and \{van den Berg\}, Anke and \{van der Wekken\}, Anthonie",

year = "2025",

month = jul,

day = "15",

language = "English",

note = "European Association for Cancer Research 2025 ; Conference date: 22-09-2025 Through 25-09-2025",

}

TY - CONF

T1 - TKI sensitivity of ROS1+ lung cancer cell lines in 2D versus 3D culturing conditions

AU - Dijkhuizen, Christa

AU - Korthuis, Patrick

AU - Aguado, Cristina

AU - Garcia-Román, Silvia

AU - Aguilar-Hernández, Andrés

AU - Drayer, Lyndsay

AU - De Looff, Margot

AU - Milder, Fin

AU - van den Berg, Anke

AU - van der Wekken, Anthonie

PY - 2025/7/15

Y1 - 2025/7/15

KW - ROS1

KW - ROS1-remmers

KW - cellijnen afkomstig van patiënten

KW - 3D-celcultuur

KW - 2D-celcultuur

KW - ROS1

KW - ROS1 inhibitors

KW - patient derived cell lines

KW - 3D cell culture

KW - 2D cell culture

M3 - Abstract

T2 - European Association for Cancer Research 2025

Y2 - 22 September 2025 through 25 September 2025

ER -