The association between sucking behavior in preterm infants and neurodevelopmental outcomes at 2 years of age

Mechteld Wolthuis, Margreet Luinge, Saakje da Costa, Wim Krijnen, Cees van der Schans, Arend Bos

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objective To evaluate whether a specific period after birth (in weeks postmenstrual age [PMA]) and specific elements of sucking are associated with abnormal neurodevelopmental outcomes at age 2 years using a longitudinal approach.
Study design Fifty-two preterm infants participated in this longitudinal cohort study (mean gestational age,
29.5 weeks; mean birth weight, 1197 g). We assessed the infants’ sucking patterns at 37-50 weeks PMA using the Neonatal Oral-Motor Assessment Scale. At age 2 years, based on a neurologic examination and the Dutch version of the Bayley Scales of Infant and Toddler Development, Second Edition, we categorized the children as developing normally (n = 39) or abnormally (n = 13). ORs, including 95% CIs, were calculated to ascertain the risk of abnormal neurodevelopmental outcomes.
Results The inability to sustain sucking at 46 weeks PMA (OR, 6.25; 95% CI, 1.29-30.35) and the absence of a
mature sucking pattern at 44 weeks PMA (OR, 6.30; 95% CI, 1.40-28.32) significantly increased the odds of
abnormal neurodevelopmental outcomes at age 2 years. The ORs of the Neonatal Oral-Motor Assessment Scale items assessing rhythmic jaw movements, rhythmic tongue movements, and coordination among sucking, swallowing, and respiration were high shortly after term, but failed to reach significance.
Conclusion Specific elements of sucking at 4-6 weeks postterm are associated with abnormal neurodevelopmental outcomes in preterm infants at age 2 years. This period might be a sensitive time of infant development in which sucking behavior is an early marker of abnormal developmental outcomes. This finding may offer opportunities for early intervention.
Original languageEnglish
Pages (from-to)1-6
JournalJournal of pediatrics
Publication statusPublished - 2014

Keywords

  • sucking behavior
  • preterm infants
  • neurodevelopmental outcomes

Cite this

@article{f06a3dc4d08b4f3b9ef9132cf2f76124,
title = "The association between sucking behavior in preterm infants and neurodevelopmental outcomes at 2 years of age",
abstract = "Objective To evaluate whether a specific period after birth (in weeks postmenstrual age [PMA]) and specific elements of sucking are associated with abnormal neurodevelopmental outcomes at age 2 years using a longitudinal approach.Study design Fifty-two preterm infants participated in this longitudinal cohort study (mean gestational age,29.5 weeks; mean birth weight, 1197 g). We assessed the infants’ sucking patterns at 37-50 weeks PMA using the Neonatal Oral-Motor Assessment Scale. At age 2 years, based on a neurologic examination and the Dutch version of the Bayley Scales of Infant and Toddler Development, Second Edition, we categorized the children as developing normally (n = 39) or abnormally (n = 13). ORs, including 95{\%} CIs, were calculated to ascertain the risk of abnormal neurodevelopmental outcomes.Results The inability to sustain sucking at 46 weeks PMA (OR, 6.25; 95{\%} CI, 1.29-30.35) and the absence of amature sucking pattern at 44 weeks PMA (OR, 6.30; 95{\%} CI, 1.40-28.32) significantly increased the odds ofabnormal neurodevelopmental outcomes at age 2 years. The ORs of the Neonatal Oral-Motor Assessment Scale items assessing rhythmic jaw movements, rhythmic tongue movements, and coordination among sucking, swallowing, and respiration were high shortly after term, but failed to reach significance.Conclusion Specific elements of sucking at 4-6 weeks postterm are associated with abnormal neurodevelopmental outcomes in preterm infants at age 2 years. This period might be a sensitive time of infant development in which sucking behavior is an early marker of abnormal developmental outcomes. This finding may offer opportunities for early intervention.",
keywords = "sucking behavior, preterm infants, neurodevelopmental outcomes, zuiggedrag, zuigmotoriek , vroeggeboorte, kinderen, neuro-ontwikkeling",
author = "Mechteld Wolthuis and Margreet Luinge and {da Costa}, Saakje and Wim Krijnen and {van der Schans}, Cees and Arend Bos",
year = "2014",
language = "English",
pages = "1--6",
journal = "Journal of pediatrics",
issn = "1097-6833",
publisher = "Mosby",

}

The association between sucking behavior in preterm infants and neurodevelopmental outcomes at 2 years of age. / Wolthuis, Mechteld; Luinge, Margreet; da Costa, Saakje; Krijnen, Wim; van der Schans, Cees; Bos, Arend.

In: Journal of pediatrics, 2014, p. 1-6.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - The association between sucking behavior in preterm infants and neurodevelopmental outcomes at 2 years of age

AU - Wolthuis, Mechteld

AU - Luinge, Margreet

AU - da Costa, Saakje

AU - Krijnen, Wim

AU - van der Schans, Cees

AU - Bos, Arend

PY - 2014

Y1 - 2014

N2 - Objective To evaluate whether a specific period after birth (in weeks postmenstrual age [PMA]) and specific elements of sucking are associated with abnormal neurodevelopmental outcomes at age 2 years using a longitudinal approach.Study design Fifty-two preterm infants participated in this longitudinal cohort study (mean gestational age,29.5 weeks; mean birth weight, 1197 g). We assessed the infants’ sucking patterns at 37-50 weeks PMA using the Neonatal Oral-Motor Assessment Scale. At age 2 years, based on a neurologic examination and the Dutch version of the Bayley Scales of Infant and Toddler Development, Second Edition, we categorized the children as developing normally (n = 39) or abnormally (n = 13). ORs, including 95% CIs, were calculated to ascertain the risk of abnormal neurodevelopmental outcomes.Results The inability to sustain sucking at 46 weeks PMA (OR, 6.25; 95% CI, 1.29-30.35) and the absence of amature sucking pattern at 44 weeks PMA (OR, 6.30; 95% CI, 1.40-28.32) significantly increased the odds ofabnormal neurodevelopmental outcomes at age 2 years. The ORs of the Neonatal Oral-Motor Assessment Scale items assessing rhythmic jaw movements, rhythmic tongue movements, and coordination among sucking, swallowing, and respiration were high shortly after term, but failed to reach significance.Conclusion Specific elements of sucking at 4-6 weeks postterm are associated with abnormal neurodevelopmental outcomes in preterm infants at age 2 years. This period might be a sensitive time of infant development in which sucking behavior is an early marker of abnormal developmental outcomes. This finding may offer opportunities for early intervention.

AB - Objective To evaluate whether a specific period after birth (in weeks postmenstrual age [PMA]) and specific elements of sucking are associated with abnormal neurodevelopmental outcomes at age 2 years using a longitudinal approach.Study design Fifty-two preterm infants participated in this longitudinal cohort study (mean gestational age,29.5 weeks; mean birth weight, 1197 g). We assessed the infants’ sucking patterns at 37-50 weeks PMA using the Neonatal Oral-Motor Assessment Scale. At age 2 years, based on a neurologic examination and the Dutch version of the Bayley Scales of Infant and Toddler Development, Second Edition, we categorized the children as developing normally (n = 39) or abnormally (n = 13). ORs, including 95% CIs, were calculated to ascertain the risk of abnormal neurodevelopmental outcomes.Results The inability to sustain sucking at 46 weeks PMA (OR, 6.25; 95% CI, 1.29-30.35) and the absence of amature sucking pattern at 44 weeks PMA (OR, 6.30; 95% CI, 1.40-28.32) significantly increased the odds ofabnormal neurodevelopmental outcomes at age 2 years. The ORs of the Neonatal Oral-Motor Assessment Scale items assessing rhythmic jaw movements, rhythmic tongue movements, and coordination among sucking, swallowing, and respiration were high shortly after term, but failed to reach significance.Conclusion Specific elements of sucking at 4-6 weeks postterm are associated with abnormal neurodevelopmental outcomes in preterm infants at age 2 years. This period might be a sensitive time of infant development in which sucking behavior is an early marker of abnormal developmental outcomes. This finding may offer opportunities for early intervention.

KW - sucking behavior

KW - preterm infants

KW - neurodevelopmental outcomes

KW - zuiggedrag

KW - zuigmotoriek

KW - vroeggeboorte

KW - kinderen

KW - neuro-ontwikkeling

M3 - Article

SP - 1

EP - 6

JO - Journal of pediatrics

JF - Journal of pediatrics

SN - 1097-6833

ER -