Synthesis of a dual-function monomer and its corresponding polymer for the valorisation of stilbenes from grape canes

A novel synthetic approach to 2,6-bis(acrylamido)pyridine (BAAPy) has been developed, producing a dual-function monomer able to self-crosslink while providing functional binding sites through its amide and pyridine groups. The monomer's structure and purity were confirmed through NMR, FTIR, and HPLC analyses. Poly(BAAPy) was subsequently synthesized and employed in the purification of stilbenes, including t-resveratrol, t-ε-viniferin, and t-piceatannol, all extracted from grape canes. These stilbenes, widely recognized for their antioxidant, antifungal, and antimicrobial properties, are valuable phytochemicals. Grape canes, a by-product of grapevine pruning, serve as a natural and cost-effective source of these bioactive compounds. Using a single-step adsorption–desorption process with an ethanol–water solvent system, the method achieved a 13-fold enrichment of stilbenes with gravimetric purities over 37%. The dual functionality of BAAPy eliminates the need for external crosslinkers and enhances adsorption capacity.