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SLC34A2-ROS1 L2026M+G2032R confers resistance to ROS1 tyrosine kinase inhibitors in Ba/F3 cells through a reduced ATP binding pocket volume

  • Christa Dijkhuizen (First author)
  • , Patrick Korthuis
  • , Juliana F. Vilachã
  • , Maaike Smelt
  • , Anthonie van der Wekken
  • , Anke van den Berg
  • , Lyndsay Drayer
  • University of Groningen, Faculty of Science and Engineering, Molecular Dynamics — Groningen Biomolecular Sciences and Biotechnology
  • University of Groningen, University Medical Center Groningen, Department of Pulmonary Medicine
  • University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology

Research output: Contribution to conference › Abstract › Academic

134 Downloads (Pure)
Original languageEnglish
Number of pages2
Publication statusPublished - 2023
EventEuropean Society for Medial Oncology 2023 Conference - Madrid, Spain
Duration: 20 Oct 2023 → 24 Oct 2023

Conference

ConferenceEuropean Society for Medial Oncology 2023 Conference
Abbreviated titleESMO2023
Country/TerritorySpain
CityMadrid
Period20/10/23 → 24/10/23

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 03 - Good Health and Well-being
    SDG 03 Good Health and Well-being

Keywords

  • ROS1
  • Ba/F3 cells
  • molecular dynamics simulation
  • ROS1 inhibitors

Research Focus Areas Hanze University of Applied Sciences * (mandatory by Hanze)

  • Healthy Ageing

Research Focus Areas Research Centre or Centre of Expertise * (mandatory by Hanze)

  • Medical Diagnostics & Point of Care Testing
  • Healthcare & Biotechnology

Publinova themes

  • Health

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