Review article – The impact of Sinogram-Affirmed Iterative Reconstruction on patient dose and image quality compared to filtered back projection: a narrative review

Paul Plasman, Astrid Bakker, René de Lange, Abdulfatah Ahmed, André Garcia, David Tomkinson, Julie Salamin, Sergey A. Buyvidovich, Alexandre Dominguez, Cosmin Campeanu, Tina Sohrabi

    Research output: Chapter in Book/Report/Conference proceedingContribution to conference proceedingAcademicpeer-review

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    Abstract

    Objective: Summarize all relevant findings in published literature regarding the potential dose reduction related to image quality using Sinogram-Affirmed Iterative Reconstruction (SAFIRE) compared to Filtered Back Projection (FBP).
    Background: Computed Tomography (CT) is one of the most used radiographic modalities in clinical practice providing high spatial and contrast resolution. However it also delivers a relatively high radiation dose to the patient. Reconstructing raw-data using Iterative Reconstruction (IR) algorithms
    has the potential to iteratively reduce image noise while maintaining or improving image quality of low dose standard FBP reconstructions. Nevertheless, long reconstruction times made IR unpractical for clinical use until recently.
    Siemens Medical developed a new IR algorithm called SAFIRE, which uses up to 5 different strength levels, and poses an alternative to the conventional IR with a significant reconstruction time reduction.
    Methods: MEDLINE, ScienceDirect and CINAHL databases were used for gathering literature. Eleven articles were included in this review (from 2012 to July 2014).
    Discussion: This narrative review summarizes the results of eleven articles (using studies on both patients and phantoms) and describes SAFIRE strengths for noise reduction in low dose acquisitions while providing acceptable image quality.
    Conclusion: Even though the results differ slightly, the literature gathered for this review suggests that the dose in current CT protocols can be reduced at least 50% while maintaining or improving image quality. There is however a lack of literature concerning paediatric population (with increased radiation
    sensitivity). Further studies should also assess the impact of SAFIRE on diagnostic accuracy.
    Original languageEnglish
    Title of host publicationOPTIMAX 2014 – radiation dose and image quality optimisation in medical imaging
    Place of PublicationLisbon, Portugal
    Pages21
    Number of pages26
    Publication statusPublished - 2015
    EventOPTIMAX 2014: radiation dose and image quality optimisation in medical imaging - Lisbon , Portugal
    Duration: 1 Aug 201431 Aug 2014

    Seminar

    SeminarOPTIMAX 2014
    Country/TerritoryPortugal
    CityLisbon
    Period1/08/1431/08/14

    Keywords

    • comparison
    • filtered back projection
    • sinogram-affirmed iterative
    • reconstruction
    • dose reduction
    • paediatric ct
    • computed tomography
    • image quality

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