Research article – A comparison of Sinogram Affirmed Iterative Reconstruction and filtered back projection on image quality and dose reduction in paediatric head CT: a phantom study

Astrid Bakker, René de Lange, Abdulfatah Ahmed, André Garcia, David Tomkinson, Julie Salamin, Sergey A. Buyvidovich, Tina Sohrabi, Alexandre Dominguez, Cosmin Campeanu

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Abstract

Background: Computed tomography (CT) is one of the most used modalities for diagnostics in paediatric populations, which is a concern as it also delivers a high patient dose. Research has focused on developing computer algorithms that provide better image quality at lower dose. The iterative reconstruction algorithm Sinogram-Affirmed Iterative Reconstruction (SAFIRE) was introduced as a new technique that reduces noise to increase image quality.
Purpose: The aim of this study is to compare SAFIRE with the current gold standard, Filtered Back Projection (FBP), and assess whether SAFIRE alone permits a reduction in dose while maintaining image quality in paediatric head CT.
Methods: Images were collected using a paediatric head phantom using a SIEMENS SOMATOM
PERSPECTIVE 128 modulated acquisition. 54 images were reconstructed using FBP and 5 different strengths of SAFIRE. Objective measures of image quality were determined by measuring SNR and CNR. Visual measures of image quality were determined by 17 observers with different radiographic experiences. Images were randomized and displayed using 2AFC; observers scored the images answering 5 questions using a Likert scale.
Results: At different dose levels, SAFIRE significantly increased SNR (up to 54%) in the acquired images compared to FBP at 80kVp (5.2-8.4), 110kVp (8.2-12.3), 130kVp (8.8-13.1). Visual image quality was higher with increasing SAFIRE strength. The highest image quality was scored with SAFIRE level 3
and higher.
Conclusion: The SAFIRE algorithm is suitable for image noise reduction in paediatric head CT. Our data demonstrates that SAFIRE enhances SNR while reducing noise with a possible reduction of dose of 68%.
Original languageEnglish
Title of host publicationOPTIMAX 2014 – radiation dose and image quality optimisation in medical imaging
Place of PublicationLisbon, Portugal
Pages28-37
Publication statusPublished - 2015
EventOPTIMAX 2014: radiation dose and image quality optimisation in medical imaging - Lisbon , Portugal
Duration: 1 Aug 201431 Aug 2014

Seminar

SeminarOPTIMAX 2014
CountryPortugal
CityLisbon
Period1/08/1431/08/14

Keywords

  • comparison
  • filtered back projection
  • sinogram-affirmed iterative
  • dose reduction
  • paediatric ct
  • computed tomography
  • image quality

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    Bakker, A., de Lange, R., Ahmed, A., Garcia, A., Tomkinson, D., Salamin, J., Buyvidovich, S. A., Sohrabi, T., Dominguez, A., & Campeanu, C. (2015). Research article – A comparison of Sinogram Affirmed Iterative Reconstruction and filtered back projection on image quality and dose reduction in paediatric head CT: a phantom study. In OPTIMAX 2014 – radiation dose and image quality optimisation in medical imaging (pp. 28-37).