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Provision of critical care for the elderly in Europe: a retrospective comparison of national healthcare frameworks in intensive care units

  • VIP2 study group
    • Paracelsus Medizinische Privatuniversity Salzburg
    • Hadassah Medical Center
    • University Hospital Dusseldorf
    • Hôpitaux de Paris, Hôpital Saint-Antoine, service de réanimation médicale
    • Department of Intensive Care Medicine, CIBER Enfermedades Respiratorias, Sabadell and Critical Care Department, Corporacion Sanitaria Universitaria Parc Tauli, Autonomous University of Barcelona, Sagrado Corazon-General de Cataluña University Hospitals, Quiron Salud
    • Department of Biomedical Sciences, Humanitas University
    • Mater Misericordiae University Hospital
    • Unidade de Cuidados Intensivos Polivalente Neurocríticos, Hospital de São José, Centro Hospitalar de Lisboa Central, Faculdade de Ciência Médicas de Lisboa, Nova Médical School
    • Ghent University
    • Geneva University Hospitals
    • Intensive Care and Perioperative Medicine Division, Jagiellonian University Medical College
    • Research Lead Critical Care Directorate St George's Hospital
    • Linköping University
    • ​Inselspital, Bern University Hospital
    • Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck
    • Department of Intensive Care, Aarhus University Hospital
    • General University Hospital of Larissa
    • Utrecht University
    • AP-HP, Hôpital Saint-Antoine, service de réanimation
    • Department of Anaesthesia and Intensive Care, Haukeland University Hospital

    Research output: Contribution to journalArticleAcademicpeer-review

    Abstract

    Objectives: In Europe, there is a distinction between two different healthcare organisation systems, the tax-based healthcare system (THS) and the social health insurance system (SHI). Our aim was to investigate whether the characteristics, treatment and mortality of older, critically ill patients in the intensive care unit (ICU) differed between THS and SHI. Setting: ICUs in 16 European countries. Participants: In total, 7817 critically ill older (≥80 years) patients were included in this study, 4941 in THS and 2876 in the SHI systems. Primary and secondary outcomes measures: We chose generalised estimation equations with robust standard errors to produce population average adjusted OR (aOR). We adjusted for patient-specific variables, health economic data, including gross domestic product (GDP) and human development index (HDI), and treatment strategies. Results: In SHI systems, there were higher rates of frail patients (Clinical Frailty Scale>4; 46% vs 41%; p<0.001), longer length of ICU stays (90±162 vs 72±134 hours; p<0.001) and increased levels of organ support. The ICU mortality (aOR 1.50, 95%CI 1.09 to 2.06; p=0.01) was consistently higher in the SHI; however, the 30-day mortality (aOR 0.89, 95%CI 0.66 to 1.21; p=0.47) was similar between THS and SHI. In a sensitivity analysis stratifying for the health economic data, the 30-day mortality was higher in SHI, in low GDP per capita (aOR 2.17, 95%CI 1.42 to 3.58) and low HDI (aOR 1.22, 95%CI 1.64 to 2.20) settings. Conclusions: The 30-day mortality was similar in both systems. Patients in SHI were older, sicker and frailer at baseline, which could be interpreted as a sign for a more liberal admission policy in SHI. We believe that the observed trend towards ICU excess mortality in SHI results mainly from a more liberal admission policy and an increase in treatment limitations.
    Original languageEnglish
    Number of pages10
    JournalBMJ Open
    Volume11
    Issue number6
    DOIs
    Publication statusPublished - 1 Jun 2021

    Keywords

    • aged
    • critical care
    • critical illness
    • delivery of health Care
    • europe
    • hospital mortality
    • humans
    • iIntensive care units
    • length of stay
    • retrospective studies

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