TY - JOUR
T1 - On the potential of wearable bioimpedance for longitudinal fluid monitoring in end-stage kidney disease
AU - Lindeboom, Lucas
AU - Lee, Seulki
AU - Wieringa, Fokko
AU - Groenendaal, Willemijn
AU - Basile, Carlo
AU - van der Sande, Frank
AU - Kooman, Jeroen
N1 - © The Author(s) 2021. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
PY - 2021/2/5
Y1 - 2021/2/5
N2 - Bioimpedance spectroscopy (BIS) has proven to be a promising non-invasive technique for fluid monitoring in haemodialysis (HD) patients. While current BIS-based monitoring of pre- and post-dialysis fluid status utilizes benchtop devices, designed for intramural use, advancements in micro-electronics have enabled the development of wearable bioimpedance systems. Wearable systems meanwhile can offer a similar frequency range for current injection as commercially available benchtop devices. This opens opportunities for unobtrusive longitudinal fluid status monitoring, including transcellular fluid shifts, with the ultimate goal of improving fluid management, thereby lowering mortality and improving quality of life for HD patients. Ultra-miniaturized wearable devices can also offer simultaneous acquisition of multiple other parameters, including haemodynamic parameters. Combination of wearable BIS and additional longitudinal multiparametric data may aid in the prevention of both haemodynamic instability as well as fluid overload. The opportunity to also acquire data during interdialytic periods using wearable devices likely will give novel pathophysiological insights and the development of smart (predicting) algorithms could contribute to personalizing dialysis schemes and ultimately to autonomous (nocturnal) home dialysis. This review provides an overview of current research regarding wearable bioimpedance, with special attention to applications in end-stage kidney disease patients. Furthermore, we present an outlook on the future use of wearable bioimpedance within dialysis practice.
AB - Bioimpedance spectroscopy (BIS) has proven to be a promising non-invasive technique for fluid monitoring in haemodialysis (HD) patients. While current BIS-based monitoring of pre- and post-dialysis fluid status utilizes benchtop devices, designed for intramural use, advancements in micro-electronics have enabled the development of wearable bioimpedance systems. Wearable systems meanwhile can offer a similar frequency range for current injection as commercially available benchtop devices. This opens opportunities for unobtrusive longitudinal fluid status monitoring, including transcellular fluid shifts, with the ultimate goal of improving fluid management, thereby lowering mortality and improving quality of life for HD patients. Ultra-miniaturized wearable devices can also offer simultaneous acquisition of multiple other parameters, including haemodynamic parameters. Combination of wearable BIS and additional longitudinal multiparametric data may aid in the prevention of both haemodynamic instability as well as fluid overload. The opportunity to also acquire data during interdialytic periods using wearable devices likely will give novel pathophysiological insights and the development of smart (predicting) algorithms could contribute to personalizing dialysis schemes and ultimately to autonomous (nocturnal) home dialysis. This review provides an overview of current research regarding wearable bioimpedance, with special attention to applications in end-stage kidney disease patients. Furthermore, we present an outlook on the future use of wearable bioimpedance within dialysis practice.
KW - humans
KW - renal dialysis/methods
KW - quality of life
KW - kidney failure, chronic/therapy
KW - water-electrolyte imbalance/etiology
KW - wearable electronic devices
KW - electric impedance
KW - mensen
KW - nierdialyse/methoden
KW - kwaliteit van leven
KW - nierfalen, chronisch/therapie
KW - water-elektrolytenonbalans/etiologie
KW - draagbare elektronische apparaten
KW - elektrische impedantie
U2 - 10.1093/ndt/gfab025
DO - 10.1093/ndt/gfab025
M3 - Review article
C2 - 33544863
SN - 0931-0509
VL - 37
SP - 2048
EP - 2054
JO - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
JF - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
IS - 11
ER -