Novel compositions and methods for trehalose phospholipids

Ildiko van Rhijn; Adriaan Minnaard; Branch  Moody; Tan-Yun Cheng; Jeffrey Buter

Novel compositions and methods for trehalose phospholipids

Ildiko van Rhijn (Inventor), Adriaan Minnaard (Inventor), Branch Moody (Inventor), Tan-Yun Cheng (Inventor), Jeffrey Buter (Inventor)

Research output: Patent › Academic

Abstract

Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6′-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.

Original language	English
Patent number	US20220119438A1
Filing date	8/01/20
Publication status	Published - 21 Apr 2022
Externally published	Yes

Keywords

vaccine
lipids
salmonella

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title = "Novel compositions and methods for trehalose phospholipids",

abstract = "Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6′-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.",

keywords = "vaccin, lipiden, vaccine, lipids, salmonella",

author = "{van Rhijn}, Ildiko and Adriaan Minnaard and Branch Moody and Tan-Yun Cheng and Jeffrey Buter",

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TY - PAT

T1 - Novel compositions and methods for trehalose phospholipids

AU - van Rhijn, Ildiko

AU - Minnaard, Adriaan

AU - Moody, Branch

AU - Cheng, Tan-Yun

AU - Buter, Jeffrey

PY - 2022/4/21

Y1 - 2022/4/21

N2 - Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6′-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.

AB - Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6′-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.

KW - vaccin

KW - lipiden

KW - vaccine

KW - lipids

KW - salmonella

M3 - Patent

M1 - US20220119438A1

Y2 - 2020/01/08

ER -

Novel compositions and methods for trehalose phospholipids

Abstract

Keywords

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