Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure

HOT-ICU Investigators

doi:10.1056/nejmoa2032510

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure

HOT-ICU Investigators

Critical Care

Krafla Magma Testbed

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Abstract Background Patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) are treated with supplemental oxygen, but the benefits and harms of different oxygenation targ...

Original language	English
Pages (from-to)	1301-1311
Number of pages	11
Journal	The New England journal of medicine
Volume	384
Issue number	14
DOIs	https://doi.org/10.1056/nejmoa2032510
Publication status	Published - 8 Apr 2021

Keywords

hypoxia/blood
intensive care units
kaplan-meier estimate
middle aged
oxygen/administration & dosage
oxygen inhalation therapy/methods
respiration, artificial/methods
respiratory distress syndrome/blood
respiratory insufficiency/blood

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10.1056/nejmoa2032510

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@article{0975784c02734fe39274e085c194f375,

title = "Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure",

abstract = "Abstract Background Patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) are treated with supplemental oxygen, but the benefits and harms of different oxygenation targ...",

keywords = "hypoxia/blood, intensive care units, kaplan-meier estimate, middle aged, oxygen/administration & dosage, oxygen inhalation therapy/methods, respiration, artificial/methods, respiratory distress syndrome/blood, respiratory insufficiency/blood, intensive care afdeling, ademhalingsfalen, ademhalingsinsuffici{\"e}ntie",

author = "{HOT-ICU Investigators} and Schj{\o}rring, {Olav L} and Klitgaard, {Thomas L} and Anders Perner and J{\o}rn Wetterslev and Theis Lange and Martin Siegemund and Minna B{\"a}cklund and Frederik Keus and Laake, {Jon H} and Matthew Morgan and Thormar, {Katrin M} and Rosborg, {S{\o}ren A} and Jannie Bisgaard and Erntgaard, {Annette E S} and Lynnerup, {Anne-Sofie H} and Pedersen, {Rasmus L} and Elena Crescioli and Gielstrup, {Theis C} and Behzadi, {Meike T} and Poulsen, {Lone M} and Stine Estrup and Laigaard, {Jens P} and Cheme Andersen and Mortensen, {Camilla B} and Brand, {Bj{\"o}rn A} and Jonathan White and Inge-Lise Jarnvig and M{\o}ller, {Morten H} and Lars Quist and Bestle, {Morten H} and Martin Sch{\o}nemann-Lund and Kamper, {Maj K} and Mathias Hindborg and Alexa Hollinger and Gebhard, {Caroline E} and N{\'u}ria Zellweger and Meyhoff, {Christian S} and Mathias Hjort and Bech, {Laura K} and Thorbj{\o}rn Gr{\o}fte and Helle Bundgaard and {\O}stergaard, {Lars H M} and Thy{\o}, {Maria A} and Thomas Hildebrandt and B{\"u}lent Uslu and S{\o}lling, {Christoffer G} and Nette M{\o}ller-Nielsen and Br{\o}chner, {Anne C} and Morten Borup and Marjatta Okkonen and Willem Dieperink",

note = "Copyright {\textcopyright} 2021 Massachusetts Medical Society.",

year = "2021",

month = apr,

day = "8",

doi = "10.1056/nejmoa2032510",

language = "English",

volume = "384",

pages = "1301--1311",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachusetts Medical Society",

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T1 - Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure

AU - HOT-ICU Investigators

AU - Schjørring, Olav L

AU - Klitgaard, Thomas L

AU - Perner, Anders

AU - Wetterslev, Jørn

AU - Lange, Theis

AU - Siegemund, Martin

AU - Bäcklund, Minna

AU - Keus, Frederik

AU - Laake, Jon H

AU - Morgan, Matthew

AU - Thormar, Katrin M

AU - Rosborg, Søren A

AU - Bisgaard, Jannie

AU - Erntgaard, Annette E S

AU - Lynnerup, Anne-Sofie H

AU - Pedersen, Rasmus L

AU - Crescioli, Elena

AU - Gielstrup, Theis C

AU - Behzadi, Meike T

AU - Poulsen, Lone M

AU - Estrup, Stine

AU - Laigaard, Jens P

AU - Andersen, Cheme

AU - Mortensen, Camilla B

AU - Brand, Björn A

AU - White, Jonathan

AU - Jarnvig, Inge-Lise

AU - Møller, Morten H

AU - Quist, Lars

AU - Bestle, Morten H

AU - Schønemann-Lund, Martin

AU - Kamper, Maj K

AU - Hindborg, Mathias

AU - Hollinger, Alexa

AU - Gebhard, Caroline E

AU - Zellweger, Núria

AU - Meyhoff, Christian S

AU - Hjort, Mathias

AU - Bech, Laura K

AU - Grøfte, Thorbjørn

AU - Bundgaard, Helle

AU - Østergaard, Lars H M

AU - Thyø, Maria A

AU - Hildebrandt, Thomas

AU - Uslu, Bülent

AU - Sølling, Christoffer G

AU - Møller-Nielsen, Nette

AU - Brøchner, Anne C

AU - Borup, Morten

AU - Okkonen, Marjatta

AU - Dieperink, Willem

PY - 2021/4/8

Y1 - 2021/4/8

N2 - Abstract Background Patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) are treated with supplemental oxygen, but the benefits and harms of different oxygenation targ...

AB - Abstract Background Patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) are treated with supplemental oxygen, but the benefits and harms of different oxygenation targ...

KW - hypoxia/blood

KW - intensive care units

KW - kaplan-meier estimate

KW - middle aged

KW - oxygen/administration & dosage

KW - oxygen inhalation therapy/methods

KW - respiration, artificial/methods

KW - respiratory distress syndrome/blood

KW - respiratory insufficiency/blood

KW - intensive care afdeling

KW - ademhalingsfalen

KW - ademhalingsinsufficiëntie

UR - https://www.mendeley.com/catalogue/1f550bb8-a8b5-32a3-908d-3be7c1f89eaa/

U2 - 10.1056/nejmoa2032510

DO - 10.1056/nejmoa2032510

M3 - Article

C2 - 33471452

SN - 0028-4793

VL - 384

SP - 1301

EP - 1311

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 14

ER -

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure

Abstract

Keywords

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