Health-related quality of life and anemia in hospitalized patients with heart failure

Imke H. Kraai, Marie Louise Luttik, P. Johansson, Dirk J. van Veldhuisen, Hans L. Hillege, Remco de Jong, Tiny Jaarsma

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

BACKGROUND: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.

METHODS: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.

RESULTS: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).

CONCLUSION: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.

Original languageEnglish
Pages (from-to)151-155
JournalInternational journal of cardiology
Volume161
Issue number3
DOIs
Publication statusPublished - 29 Nov 2012

Keywords

  • anemia
  • health status
  • heart failures
  • hospitalization
  • quality of life
  • hemoglobin

Cite this

Kraai, I. H., Luttik, M. L., Johansson, P., van Veldhuisen, D. J., Hillege, H. L., de Jong, R., & Jaarsma, T. (2012). Health-related quality of life and anemia in hospitalized patients with heart failure. International journal of cardiology, 161(3), 151-155. https://doi.org/10.1016/j.ijcard.2012.05.036
Kraai, Imke H. ; Luttik, Marie Louise ; Johansson, P. ; van Veldhuisen, Dirk J. ; Hillege, Hans L. ; de Jong, Remco ; Jaarsma, Tiny. / Health-related quality of life and anemia in hospitalized patients with heart failure. In: International journal of cardiology. 2012 ; Vol. 161, No. 3. pp. 151-155.
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abstract = "BACKGROUND: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.METHODS: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.RESULTS: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70{\%} of these patients had no anemia (n=712), 14{\%} had mild anemia (n=141), and 16{\%} had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).CONCLUSION: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.",
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Kraai, IH, Luttik, ML, Johansson, P, van Veldhuisen, DJ, Hillege, HL, de Jong, R & Jaarsma, T 2012, 'Health-related quality of life and anemia in hospitalized patients with heart failure' International journal of cardiology, vol. 161, no. 3, pp. 151-155. https://doi.org/10.1016/j.ijcard.2012.05.036

Health-related quality of life and anemia in hospitalized patients with heart failure. / Kraai, Imke H.; Luttik, Marie Louise; Johansson, P.; van Veldhuisen, Dirk J.; Hillege, Hans L.; de Jong, Remco; Jaarsma, Tiny.

In: International journal of cardiology, Vol. 161, No. 3, 29.11.2012, p. 151-155.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Health-related quality of life and anemia in hospitalized patients with heart failure

AU - Kraai, Imke H.

AU - Luttik, Marie Louise

AU - Johansson, P.

AU - van Veldhuisen, Dirk J.

AU - Hillege, Hans L.

AU - de Jong, Remco

AU - Jaarsma, Tiny

N1 - Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

PY - 2012/11/29

Y1 - 2012/11/29

N2 - BACKGROUND: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.METHODS: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.RESULTS: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).CONCLUSION: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.

AB - BACKGROUND: Anemia is a serious and highly prevalent co-morbidity in chronic heart failure (HF) patients. Its influence on health-related quality of life (HR-QoL) has rarely been studied, and no data is available regarding the role it plays in hospitalized HF patients.METHODS: Baseline data from the COACH study (Coordinating study evaluating Outcomes of Advising and Counselling in Heart Failure) were used. HR-QoL was assessed by means of generic and disease-specific questionnaires. Analyses were performed using ANOVA and ANCOVA, with covariates of age, gender, eGFR, diabetes, and NYHA class.RESULTS: In total, 1013 hospitalized patients with a mean age of 71 (SD 11) years were included; 70% of these patients had no anemia (n=712), 14% had mild anemia (n=141), and 16% had moderate-to-severe anemia (n=160). Independent associations were found between anemia and physical functioning (p=0.019), anemia and role limitations due to physical functioning (p=0.002), anemia and general health (p=0.024), and anemia and global well-being (p=0.003).CONCLUSION: In addition to the burden of HF itself, anemia is an important factor which influences HR-QoL in hospitalized HF patients, and one that is most pronounced in the domain related to physical functioning and general health.

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KW - health status

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KW - hospitalization

KW - quality of life

KW - hemoglobin

KW - bejaarden

KW - anemie

KW - gezondheidsstatus

KW - hartfalen

KW - ziekenhuisopname

KW - kwaliteit van leven

U2 - 10.1016/j.ijcard.2012.05.036

DO - 10.1016/j.ijcard.2012.05.036

M3 - Article

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JO - International journal of cardiology

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