Abstract
Small RNAs are important regulators of genome function, yet their prediction in genomes is still a major computational challenge. Statistical analyses of pre-miRNA sequences indicated that their 2D structure tends to have a minimal free energy (MFE) significantly lower than MFE values of equivalently randomized sequences with the same nucleotide composition, in contrast to other classes of non-coding RNA. The computation of many MFEs is, however, too intensive to allow for genome-wide screenings.
| Original language | English |
|---|---|
| Number of pages | 10 |
| Journal | BMC Research Notes |
| Publication status | Published - 13 Jan 2014 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 07 Affordable and Clean Energy -
SDG 09 Industry, Innovation, and Infrastructure
Keywords
- energy
- grid computing
- molecular techniques
Research Focus Areas Hanze University of Applied Sciences * (mandatory by Hanze)
- Energy
Research Focus Areas Research Centre or Centre of Expertise * (mandatory by Hanze)
- Renewable fuels and sustainable gases
Publinova themes
- Technology
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