Effect of forced expirations on mucus clearance in patients with chronic airflow obstruction: effect of lung recoil pressure

Cees van der Schans, D A Piers, H Beekhuis, G. H. Koëter, T W van der Mark, D S Postma

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Spontaneous mucus clearance and the effect of forced expirations and coughing on mucus clearance were investigated in eight patients with chronic airflow obstruction and low elastic recoil pressure (emphysema group: mean FEV1 45% predicted) and in seven patients with chronic airflow obstruction and normal elastic recoil pressure (chronic bronchitis group: mean FEV1 57% predicted). Mucus clearance was measured in a central and a peripheral lung region by a radioactive aerosol tracer technique. Spontaneous mucus clearance from the peripheral lung region was higher in the patients with emphysema than in those with chronic bronchitis. There was no difference in central mucus clearance between the two groups. Mucus clearance from the peripheral lung region increased significantly during forced expirations and coughing in the patients with chronic bronchitis but not in those with emphysema. It is concluded that in patients with chronic airflow obstruction and regular sputum production spontaneous peripheral mucus clearance is greater in those with decreased elastic recoil pressure. Physiotherapy that includes forced expirations and coughing can enhance mucus clearance in such patients when elastic recoil pressure is normal but is unlikely to be effective when elastic recoil pressure is decreased.

Original languageEnglish
Pages (from-to)623-627
JournalThorax
Volume45
Issue number8
DOIs
Publication statusPublished - Sep 1990
Externally publishedYes

Keywords

  • adults
  • bronchitis
  • lung diseases, obstructive
  • pulmonary emphysema

Cite this

van der Schans, Cees ; Piers, D A ; Beekhuis, H ; Koëter, G. H. ; van der Mark, T W ; Postma, D S. / Effect of forced expirations on mucus clearance in patients with chronic airflow obstruction : effect of lung recoil pressure. In: Thorax. 1990 ; Vol. 45, No. 8. pp. 623-627.
@article{1f171b6273194e57a655077d9c8a5f7f,
title = "Effect of forced expirations on mucus clearance in patients with chronic airflow obstruction: effect of lung recoil pressure",
abstract = "Spontaneous mucus clearance and the effect of forced expirations and coughing on mucus clearance were investigated in eight patients with chronic airflow obstruction and low elastic recoil pressure (emphysema group: mean FEV1 45{\%} predicted) and in seven patients with chronic airflow obstruction and normal elastic recoil pressure (chronic bronchitis group: mean FEV1 57{\%} predicted). Mucus clearance was measured in a central and a peripheral lung region by a radioactive aerosol tracer technique. Spontaneous mucus clearance from the peripheral lung region was higher in the patients with emphysema than in those with chronic bronchitis. There was no difference in central mucus clearance between the two groups. Mucus clearance from the peripheral lung region increased significantly during forced expirations and coughing in the patients with chronic bronchitis but not in those with emphysema. It is concluded that in patients with chronic airflow obstruction and regular sputum production spontaneous peripheral mucus clearance is greater in those with decreased elastic recoil pressure. Physiotherapy that includes forced expirations and coughing can enhance mucus clearance in such patients when elastic recoil pressure is normal but is unlikely to be effective when elastic recoil pressure is decreased.",
keywords = "adults, bronchitis, lung diseases, obstructive, pulmonary emphysema, bronchitis, longziekten, pulmonaire emfyseem",
author = "{van der Schans}, Cees and Piers, {D A} and H Beekhuis and Ko{\"e}ter, {G. H.} and {van der Mark}, {T W} and Postma, {D S}",
year = "1990",
month = "9",
doi = "10.1136/thx.45.8.623",
language = "English",
volume = "45",
pages = "623--627",
journal = "Thorax",
issn = "0040-6376",
publisher = "BMJ Publishing Group",
number = "8",

}

Effect of forced expirations on mucus clearance in patients with chronic airflow obstruction : effect of lung recoil pressure. / van der Schans, Cees; Piers, D A; Beekhuis, H; Koëter, G. H.; van der Mark, T W; Postma, D S.

In: Thorax, Vol. 45, No. 8, 09.1990, p. 623-627.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Effect of forced expirations on mucus clearance in patients with chronic airflow obstruction

T2 - effect of lung recoil pressure

AU - van der Schans, Cees

AU - Piers, D A

AU - Beekhuis, H

AU - Koëter, G. H.

AU - van der Mark, T W

AU - Postma, D S

PY - 1990/9

Y1 - 1990/9

N2 - Spontaneous mucus clearance and the effect of forced expirations and coughing on mucus clearance were investigated in eight patients with chronic airflow obstruction and low elastic recoil pressure (emphysema group: mean FEV1 45% predicted) and in seven patients with chronic airflow obstruction and normal elastic recoil pressure (chronic bronchitis group: mean FEV1 57% predicted). Mucus clearance was measured in a central and a peripheral lung region by a radioactive aerosol tracer technique. Spontaneous mucus clearance from the peripheral lung region was higher in the patients with emphysema than in those with chronic bronchitis. There was no difference in central mucus clearance between the two groups. Mucus clearance from the peripheral lung region increased significantly during forced expirations and coughing in the patients with chronic bronchitis but not in those with emphysema. It is concluded that in patients with chronic airflow obstruction and regular sputum production spontaneous peripheral mucus clearance is greater in those with decreased elastic recoil pressure. Physiotherapy that includes forced expirations and coughing can enhance mucus clearance in such patients when elastic recoil pressure is normal but is unlikely to be effective when elastic recoil pressure is decreased.

AB - Spontaneous mucus clearance and the effect of forced expirations and coughing on mucus clearance were investigated in eight patients with chronic airflow obstruction and low elastic recoil pressure (emphysema group: mean FEV1 45% predicted) and in seven patients with chronic airflow obstruction and normal elastic recoil pressure (chronic bronchitis group: mean FEV1 57% predicted). Mucus clearance was measured in a central and a peripheral lung region by a radioactive aerosol tracer technique. Spontaneous mucus clearance from the peripheral lung region was higher in the patients with emphysema than in those with chronic bronchitis. There was no difference in central mucus clearance between the two groups. Mucus clearance from the peripheral lung region increased significantly during forced expirations and coughing in the patients with chronic bronchitis but not in those with emphysema. It is concluded that in patients with chronic airflow obstruction and regular sputum production spontaneous peripheral mucus clearance is greater in those with decreased elastic recoil pressure. Physiotherapy that includes forced expirations and coughing can enhance mucus clearance in such patients when elastic recoil pressure is normal but is unlikely to be effective when elastic recoil pressure is decreased.

KW - adults

KW - bronchitis

KW - lung diseases, obstructive

KW - pulmonary emphysema

KW - bronchitis

KW - longziekten

KW - pulmonaire emfyseem

UR - http://www.mendeley.com/research/effect-forced-expirations-mucus-clearance-patients-chronic-airflow-obstruction-effect-lung-recoil-pr

U2 - 10.1136/thx.45.8.623

DO - 10.1136/thx.45.8.623

M3 - Article

VL - 45

SP - 623

EP - 627

JO - Thorax

JF - Thorax

SN - 0040-6376

IS - 8

ER -