Development of a modular photoreactor for the upscaling of continuous flow photochemistry

Johannes G.H. Hermens; Mathieu Lepage; Arjan Kloekhorst; Erik Keller; Ben L. Feringa; Robin Bloem; Maurice Meijer

doi:DOI	https://doi.org/10.1039/D2RE00310D

Development of a modular photoreactor for the upscaling of continuous flow photochemistry

Johannes G.H. Hermens (First author), Mathieu Lepage, Arjan Kloekhorst, Erik Keller, Ben L. Feringa, Robin Bloem, Maurice Meijer

Stratingh Institute, University of Groningen

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The upscaling of biphasic photochemical reactions is challenging because of the inherent constraints of liquid-gas mixing and light penetration. Using semi-permeable coaxial flow chemistry within a modular photoreactor, the photooxidation of the platform chemical furfural was scaled up to produce routinely 29 gram per day of biobased building block hydroxybutenolide, a precursor to acrylate alternatives.

Original language	English
Pages (from-to)	2280-2284
Number of pages	5
Journal	Reaction Chemistry & Engineering
Volume	7
Issue number	11
DOIs	https://doi.org/DOI https://doi.org/10.1039/D2RE00310D https://doi.org/10.1039/d2re00310d
Publication status	Published - 28 Sep 2022

Keywords

modular photoreactor
continuous flow photochemistry
upscaling

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DOI https://doi.org/10.1039/D2RE00310DLicence: Unspecified
10.1039/d2re00310dLicence: CC BY-NC

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AU - Hermens, Johannes G.H.

AU - Lepage, Mathieu

AU - Kloekhorst, Arjan

AU - Keller, Erik

AU - Feringa, Ben L.

AU - Bloem, Robin

AU - Meijer, Maurice

PY - 2022/9/28

Y1 - 2022/9/28

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AB - The upscaling of biphasic photochemical reactions is challenging because of the inherent constraints of liquid-gas mixing and light penetration. Using semi-permeable coaxial flow chemistry within a modular photoreactor, the photooxidation of the platform chemical furfural was scaled up to produce routinely 29 gram per day of biobased building block hydroxybutenolide, a precursor to acrylate alternatives.

KW - modular photoreactor

KW - continuous flow photochemistry

KW - upscaling

KW - modulaire fotoreactor

KW - continue fotochemie

KW - opschalen

U2 - DOI https://doi.org/10.1039/D2RE00310D

DO - DOI https://doi.org/10.1039/D2RE00310D

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JF - Reaction Chemistry & Engineering

SN - 2058-9883

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ER -

Development of a modular photoreactor for the upscaling of continuous flow photochemistry

Abstract

Keywords

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