Content validity across methods of malnutrition assessment in patients with cancer is limited

Martine Sealy, Willemke Nijholt, M.M. Stuiver, M.M. van der Berg, Jan Roodenburg, Faith D. Ottery, Cees van der Schans, Harriët Jager

Research output: Contribution to journalArticleAcademicpeer-review


To identify malnutrition assessment methods in cancer patients and assess their content validity based on internationally accepted definitions for malnutrition.
Study Design and Setting
Systematic review of studies in cancer patients that operationalized malnutrition as a variable, published since 1998. Eleven key concepts, within the three domains reflected by the malnutrition definitions acknowledged by European Society for Clinical Nutrition and Metabolism (ESPEN) and the American Society for Parenteral and Enteral Nutrition (ASPEN): A: nutrient balance; B: changes in body shape, body area and body composition; and C: function, were used to classify content validity of methods to assess malnutrition. Content validity indices (M-CVIA–C) were calculated per assessment method. Acceptable content validity was defined as M-CVIA–C ≥ 0.80.
Original languageEnglish
Pages (from-to)125-136
JournalJournal of clinical epidemiology
Publication statusPublished - 27 Feb 2016



  • content validity
  • malnutrition
  • cancer

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