Causes and consequences of interdialytic weight gain

Karin J R Ipema, Johanna Kuipers, Ralf Westerhuis, Carlo A J M Gaillard, Cees P van der Schans, Wim P Krijnen, Casper F M Franssen

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

BACKGROUND/AIMS: Higher interdialytic weight gain (IDWG) is associated with higher predialysis blood pressure and increased mortality. IDWG is also increasingly being recognized as an indicator of nutritional status. We studied in detail the associations of various patient factors and nutritional parameters with IDWG.

METHODS: We collected data during one week for IDWG and hemodynamic parameters in 138 prevalent adult haemodialysis patients on a thrice-weekly haemodialysis schedule. A multivariate linear regression analysis was employed to identify factors that are associated with IDWG.

RESULTS: The mean (±SD) age was 62.5 (±18.2) years, 36% were female, 36% had diuresis, and 23% had diabetes. Patients in the highest IDWG tertile were significantly younger, more frequently male, and had a significantly higher subjective global assessment score (SGA). A higher IDWG as a percentage of body weight (%IDWG) was associated with a younger age, greater height and weight, absence of diuresis, and lower postdialysis plasma sodium levels. The model with these five parameters explained 37% of the variance of %IDWG. Predialysis, intradialysis, and postdialysis diastolic blood pressure was significantly higher in the highest tertile of IDWG.

CONCLUSION: The most important associations of %IDWG are age, height, weight, diuresis, and postdialysis sodium. Patients with the highest IDWG have significantly higher diastolic blood pressures.

Original languageEnglish
Pages (from-to)710-720
JournalKidney & blood pressure research
Volume41
Issue number5
DOIs
Publication statusPublished - 2016

Keywords

  • haemodialysis
  • age factors
  • blood pressure
  • nutritional status
  • weight gain

Cite this

Ipema, K. J. R., Kuipers, J., Westerhuis, R., Gaillard, C. A. J. M., van der Schans, C. P., Krijnen, W. P., & Franssen, C. F. M. (2016). Causes and consequences of interdialytic weight gain. Kidney & blood pressure research, 41(5), 710-720. https://doi.org/10.1159/000450560
Ipema, Karin J R ; Kuipers, Johanna ; Westerhuis, Ralf ; Gaillard, Carlo A J M ; van der Schans, Cees P ; Krijnen, Wim P ; Franssen, Casper F M. / Causes and consequences of interdialytic weight gain. In: Kidney & blood pressure research. 2016 ; Vol. 41, No. 5. pp. 710-720.
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abstract = "BACKGROUND/AIMS: Higher interdialytic weight gain (IDWG) is associated with higher predialysis blood pressure and increased mortality. IDWG is also increasingly being recognized as an indicator of nutritional status. We studied in detail the associations of various patient factors and nutritional parameters with IDWG.METHODS: We collected data during one week for IDWG and hemodynamic parameters in 138 prevalent adult haemodialysis patients on a thrice-weekly haemodialysis schedule. A multivariate linear regression analysis was employed to identify factors that are associated with IDWG.RESULTS: The mean (±SD) age was 62.5 (±18.2) years, 36{\%} were female, 36{\%} had diuresis, and 23{\%} had diabetes. Patients in the highest IDWG tertile were significantly younger, more frequently male, and had a significantly higher subjective global assessment score (SGA). A higher IDWG as a percentage of body weight ({\%}IDWG) was associated with a younger age, greater height and weight, absence of diuresis, and lower postdialysis plasma sodium levels. The model with these five parameters explained 37{\%} of the variance of {\%}IDWG. Predialysis, intradialysis, and postdialysis diastolic blood pressure was significantly higher in the highest tertile of IDWG.CONCLUSION: The most important associations of {\%}IDWG are age, height, weight, diuresis, and postdialysis sodium. Patients with the highest IDWG have significantly higher diastolic blood pressures.",
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Ipema, KJR, Kuipers, J, Westerhuis, R, Gaillard, CAJM, van der Schans, CP, Krijnen, WP & Franssen, CFM 2016, 'Causes and consequences of interdialytic weight gain' Kidney & blood pressure research, vol. 41, no. 5, pp. 710-720. https://doi.org/10.1159/000450560

Causes and consequences of interdialytic weight gain. / Ipema, Karin J R; Kuipers, Johanna; Westerhuis, Ralf; Gaillard, Carlo A J M; van der Schans, Cees P; Krijnen, Wim P; Franssen, Casper F M.

In: Kidney & blood pressure research, Vol. 41, No. 5, 2016, p. 710-720.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Ipema, Karin J R

AU - Kuipers, Johanna

AU - Westerhuis, Ralf

AU - Gaillard, Carlo A J M

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AU - Krijnen, Wim P

AU - Franssen, Casper F M

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N2 - BACKGROUND/AIMS: Higher interdialytic weight gain (IDWG) is associated with higher predialysis blood pressure and increased mortality. IDWG is also increasingly being recognized as an indicator of nutritional status. We studied in detail the associations of various patient factors and nutritional parameters with IDWG.METHODS: We collected data during one week for IDWG and hemodynamic parameters in 138 prevalent adult haemodialysis patients on a thrice-weekly haemodialysis schedule. A multivariate linear regression analysis was employed to identify factors that are associated with IDWG.RESULTS: The mean (±SD) age was 62.5 (±18.2) years, 36% were female, 36% had diuresis, and 23% had diabetes. Patients in the highest IDWG tertile were significantly younger, more frequently male, and had a significantly higher subjective global assessment score (SGA). A higher IDWG as a percentage of body weight (%IDWG) was associated with a younger age, greater height and weight, absence of diuresis, and lower postdialysis plasma sodium levels. The model with these five parameters explained 37% of the variance of %IDWG. Predialysis, intradialysis, and postdialysis diastolic blood pressure was significantly higher in the highest tertile of IDWG.CONCLUSION: The most important associations of %IDWG are age, height, weight, diuresis, and postdialysis sodium. Patients with the highest IDWG have significantly higher diastolic blood pressures.

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KW - nutritional status

KW - weight gain

KW - hemodialyse

KW - leeftijdsfactoren

KW - bloeddruk

KW - voedingstoestand

KW - gewichtstoename

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