Application of ultrasound for muscle assessment in sarcopenia: towards standardized measurements

Stany Perkisas (First author), Stephan Bakker, Juergen Bauer, David Beckwee, Anne-Marie De Cock, Johannes Hobbelen, Harriët Jager-Wittenaar, Agnieszka Kasiukiewicz, Francesco Landi, Ester Marco, Ana Merello, Karolina Piotrowicz, Elisabet Sanchez, Dolores Sanchez-Rodriguez, Aldo Scafoglieri, Alfonso Cruz-Jentoft, Maurits Vandewoude

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Purpose: Measurement of muscle mass is paramount in the screening and diagnosis of sarcopenia. Besides muscle quantity however, also quality assessment is important. Ultrasonography (US) has the advantage over dual-energy X-ray absorptiometry (DEXA) and bio-impedance analysis (BIA) to give both quantitative and qualitative information on muscle. However, before its use in clinical practice, several methodological aspects still need to be addressed. Both standardization in measurement techniques and the availability of reference values are currently lacking. This review aims to provide an evidence-based standardization of assessing appendicular muscle with the use of US. Methods: A systematic review was performed for ultrasonography to assess muscle in older people. Pubmed, SCOPUS and Web of Sciences were searched. All articles regarding the use of US in assessing appendicular muscle were used. Description of US-specific parameters and localization of the measurement were retrieved. Results: Through this process, five items of muscle assessment were identified in the evaluated articles: thickness, cross-sectional area, echogenicity, fascicle length and pennation angle. Different techniques for measurement and location of measurement used were noted, as also the different muscles in which this was evaluated. Then, a translation for a clinical setting in a standardized way was proposed. Conclusions: The results of this review provide thus an evidence base for an ultrasound protocol in the assessment of skeletal muscle. This standardization of measurements is the first step in creating conditions to further test the applicability of US for use on a large scale as a routine assessment and follow-up tool for appendicular muscle.
Original languageEnglish
Pages (from-to)739-757
JournalEuropean geriatric medicine
Volume9
Issue number6
DOIs
Publication statusPublished - 1 Dec 2018

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Sarcopenia
Muscles
Ultrasonography
Photon Absorptiometry
Electric Impedance
PubMed
Reference Values
Skeletal Muscle

Keywords

  • muscle assessment
  • sarcopenia
  • ultrasound

Cite this

Perkisas, Stany ; Bakker, Stephan ; Bauer, Juergen ; Beckwee, David ; De Cock, Anne-Marie ; Hobbelen, Johannes ; Jager-Wittenaar, Harriët ; Kasiukiewicz, Agnieszka ; Landi, Francesco ; Marco, Ester ; Merello, Ana ; Piotrowicz, Karolina ; Sanchez, Elisabet ; Sanchez-Rodriguez, Dolores ; Scafoglieri, Aldo ; Cruz-Jentoft, Alfonso ; Vandewoude, Maurits. / Application of ultrasound for muscle assessment in sarcopenia: towards standardized measurements. In: European geriatric medicine. 2018 ; Vol. 9, No. 6. pp. 739-757.
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abstract = "Purpose: Measurement of muscle mass is paramount in the screening and diagnosis of sarcopenia. Besides muscle quantity however, also quality assessment is important. Ultrasonography (US) has the advantage over dual-energy X-ray absorptiometry (DEXA) and bio-impedance analysis (BIA) to give both quantitative and qualitative information on muscle. However, before its use in clinical practice, several methodological aspects still need to be addressed. Both standardization in measurement techniques and the availability of reference values are currently lacking. This review aims to provide an evidence-based standardization of assessing appendicular muscle with the use of US. Methods: A systematic review was performed for ultrasonography to assess muscle in older people. Pubmed, SCOPUS and Web of Sciences were searched. All articles regarding the use of US in assessing appendicular muscle were used. Description of US-specific parameters and localization of the measurement were retrieved. Results: Through this process, five items of muscle assessment were identified in the evaluated articles: thickness, cross-sectional area, echogenicity, fascicle length and pennation angle. Different techniques for measurement and location of measurement used were noted, as also the different muscles in which this was evaluated. Then, a translation for a clinical setting in a standardized way was proposed. Conclusions: The results of this review provide thus an evidence base for an ultrasound protocol in the assessment of skeletal muscle. This standardization of measurements is the first step in creating conditions to further test the applicability of US for use on a large scale as a routine assessment and follow-up tool for appendicular muscle.",
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Perkisas, S, Bakker, S, Bauer, J, Beckwee, D, De Cock, A-M, Hobbelen, J, Jager-Wittenaar, H, Kasiukiewicz, A, Landi, F, Marco, E, Merello, A, Piotrowicz, K, Sanchez, E, Sanchez-Rodriguez, D, Scafoglieri, A, Cruz-Jentoft, A & Vandewoude, M 2018, 'Application of ultrasound for muscle assessment in sarcopenia: towards standardized measurements', European geriatric medicine, vol. 9, no. 6, pp. 739-757. https://doi.org/10.1007/s41999-018-0104-9

Application of ultrasound for muscle assessment in sarcopenia: towards standardized measurements. / Perkisas, Stany (First author); Bakker, Stephan; Bauer, Juergen; Beckwee, David; De Cock, Anne-Marie; Hobbelen, Johannes; Jager-Wittenaar, Harriët; Kasiukiewicz, Agnieszka; Landi, Francesco; Marco, Ester; Merello, Ana; Piotrowicz, Karolina; Sanchez, Elisabet; Sanchez-Rodriguez, Dolores; Scafoglieri, Aldo; Cruz-Jentoft, Alfonso; Vandewoude, Maurits.

In: European geriatric medicine, Vol. 9, No. 6, 01.12.2018, p. 739-757.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Application of ultrasound for muscle assessment in sarcopenia: towards standardized measurements

AU - Perkisas, Stany

AU - Bakker, Stephan

AU - Bauer, Juergen

AU - Beckwee, David

AU - De Cock, Anne-Marie

AU - Hobbelen, Johannes

AU - Jager-Wittenaar, Harriët

AU - Kasiukiewicz, Agnieszka

AU - Landi, Francesco

AU - Marco, Ester

AU - Merello, Ana

AU - Piotrowicz, Karolina

AU - Sanchez, Elisabet

AU - Sanchez-Rodriguez, Dolores

AU - Scafoglieri, Aldo

AU - Cruz-Jentoft, Alfonso

AU - Vandewoude, Maurits

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Purpose: Measurement of muscle mass is paramount in the screening and diagnosis of sarcopenia. Besides muscle quantity however, also quality assessment is important. Ultrasonography (US) has the advantage over dual-energy X-ray absorptiometry (DEXA) and bio-impedance analysis (BIA) to give both quantitative and qualitative information on muscle. However, before its use in clinical practice, several methodological aspects still need to be addressed. Both standardization in measurement techniques and the availability of reference values are currently lacking. This review aims to provide an evidence-based standardization of assessing appendicular muscle with the use of US. Methods: A systematic review was performed for ultrasonography to assess muscle in older people. Pubmed, SCOPUS and Web of Sciences were searched. All articles regarding the use of US in assessing appendicular muscle were used. Description of US-specific parameters and localization of the measurement were retrieved. Results: Through this process, five items of muscle assessment were identified in the evaluated articles: thickness, cross-sectional area, echogenicity, fascicle length and pennation angle. Different techniques for measurement and location of measurement used were noted, as also the different muscles in which this was evaluated. Then, a translation for a clinical setting in a standardized way was proposed. Conclusions: The results of this review provide thus an evidence base for an ultrasound protocol in the assessment of skeletal muscle. This standardization of measurements is the first step in creating conditions to further test the applicability of US for use on a large scale as a routine assessment and follow-up tool for appendicular muscle.

AB - Purpose: Measurement of muscle mass is paramount in the screening and diagnosis of sarcopenia. Besides muscle quantity however, also quality assessment is important. Ultrasonography (US) has the advantage over dual-energy X-ray absorptiometry (DEXA) and bio-impedance analysis (BIA) to give both quantitative and qualitative information on muscle. However, before its use in clinical practice, several methodological aspects still need to be addressed. Both standardization in measurement techniques and the availability of reference values are currently lacking. This review aims to provide an evidence-based standardization of assessing appendicular muscle with the use of US. Methods: A systematic review was performed for ultrasonography to assess muscle in older people. Pubmed, SCOPUS and Web of Sciences were searched. All articles regarding the use of US in assessing appendicular muscle were used. Description of US-specific parameters and localization of the measurement were retrieved. Results: Through this process, five items of muscle assessment were identified in the evaluated articles: thickness, cross-sectional area, echogenicity, fascicle length and pennation angle. Different techniques for measurement and location of measurement used were noted, as also the different muscles in which this was evaluated. Then, a translation for a clinical setting in a standardized way was proposed. Conclusions: The results of this review provide thus an evidence base for an ultrasound protocol in the assessment of skeletal muscle. This standardization of measurements is the first step in creating conditions to further test the applicability of US for use on a large scale as a routine assessment and follow-up tool for appendicular muscle.

KW - spieren

KW - sarcopenia

KW - echografie

KW - ultrageluid

KW - muscle assessment

KW - sarcopenia

KW - ultrasound

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M3 - Article

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EP - 757

JO - European geriatric medicine

JF - European geriatric medicine

SN - 1878-7649

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ER -