Allosterically driven multicomponent assembly

Pall Thordarson, Ruud G.E. Coumans, Johannes A.A.W. Elemans, Johan Visser, Paul J. Thomassen, Alan E. Rowan, Roeland J.M. Nolte

Research output: Contribution to journalArticleAcademicpeer-review


Bound to cooperate: Binding of dimethylviologen in the cavity of a Zn porphyrin host dramatically increases the affinity of the host for N-donating ligands and vice versa (see scheme). These positive heterotropic allosteric effects are exploited to direct complex equilibrium mixtures towards a single self-assembled species. This allosteric magnification was used to obtain a pentameric sandwich architecture from a complex mixture of components.
Original languageEnglish
Pages (from-to)4755-4759
Number of pages5
JournalAngewandte Chemie International Edition
Issue number36
Publication statusPublished - 7 Sept 2004
Externally publishedYes


  • allosterische effecten
  • dimethylviologen
  • chemische verbindingen
  • multicomponenten


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