Abstract
Background
Mindfulness Based Cognitive Therapy (MBCT) has been shown to reduce the risk of relapse in patients with recurrent depression, but relapse rates remain high. To further improve outcome for this group of patients, follow-up interventions may be needed. Compassion training focuses explicitly on developing self-compassion, one of the putative working mechanisms of MBCT. No previous research has been done on the effectiveness of compassion training following MBCT in patients with recurrent depression.
Aims
To investigate the effectiveness of Mindfulness-Based Compassionate Living (MBCL) in reducing (residual) depressive symptoms in patients with recurrent depression who previously participated in MBCT.
Methods/design
A randomized controlled trial comparing MBCL in addition to treatment as usual (TAU) with TAU only, in patients suffering from recurrent depressive episodes who completed an MBCT course in the past. Assessments will take place at baseline, post-treatment and at six months follow-up. After the control period, patients randomized to the TAU condition will be offered MBCL as well.
Outcome measures
Primary outcome measure is severity of depressive symptoms according to the Beck Depression Inventory-II (BDI-II) at post-treatment. Secondary outcome measures are presence or absence of DSM-IV depressive disorder, rumination, self-compassion, mindfulness skills, positive affect, quality of life, experiential avoidance and fear of self-compassion.
Discussion
Our study is the first randomized controlled trial to examine the effectiveness of compassion training following MBCT in a recurrently depressed population.
Trial registration
ClinicalTrials.gov: NCT02059200, registered 30 January 2014.
Mindfulness Based Cognitive Therapy (MBCT) has been shown to reduce the risk of relapse in patients with recurrent depression, but relapse rates remain high. To further improve outcome for this group of patients, follow-up interventions may be needed. Compassion training focuses explicitly on developing self-compassion, one of the putative working mechanisms of MBCT. No previous research has been done on the effectiveness of compassion training following MBCT in patients with recurrent depression.
Aims
To investigate the effectiveness of Mindfulness-Based Compassionate Living (MBCL) in reducing (residual) depressive symptoms in patients with recurrent depression who previously participated in MBCT.
Methods/design
A randomized controlled trial comparing MBCL in addition to treatment as usual (TAU) with TAU only, in patients suffering from recurrent depressive episodes who completed an MBCT course in the past. Assessments will take place at baseline, post-treatment and at six months follow-up. After the control period, patients randomized to the TAU condition will be offered MBCL as well.
Outcome measures
Primary outcome measure is severity of depressive symptoms according to the Beck Depression Inventory-II (BDI-II) at post-treatment. Secondary outcome measures are presence or absence of DSM-IV depressive disorder, rumination, self-compassion, mindfulness skills, positive affect, quality of life, experiential avoidance and fear of self-compassion.
Discussion
Our study is the first randomized controlled trial to examine the effectiveness of compassion training following MBCT in a recurrently depressed population.
Trial registration
ClinicalTrials.gov: NCT02059200, registered 30 January 2014.
| Translated title of the contribution | Een parallel-groep, gerandomiseerde gecontroleerde trial over de effectiviteit van mindfulness based compassievol leven (MBCL) vergeleken met gebruikelijke behandeling bij terugkerende depressie: trial ontwerp en protocol. |
|---|---|
| Original language | English |
| Article number | 50 |
| Pages (from-to) | 77-83 |
| Number of pages | 7 |
| Journal | Contemporary Clinical Trials |
| Volume | 50 |
| DOIs | |
| Publication status | Published - Sept 2016 |
| Externally published | Yes |
Keywords
- mindfulness based cognitive therapy
- recurrent depression
- mindfulness based compassionate living
- randomized controlled trial